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Extensive subclonal mutational diversity in human colorectal cancer and its significance.
Loeb LA, Kohrn BF, Loubet-Senear KJ, Dunn YJ, Ahn EH, O'Sullivan JN, Salk JJ, Bronner MP, Beckman RA. Loeb LA, et al. Among authors: loubet senear kj. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26863-26872. doi: 10.1073/pnas.1910301116. Epub 2019 Dec 5. Proc Natl Acad Sci U S A. 2019. PMID: 31806761 Free PMC article.
Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan.
Salk JJ, Loubet-Senear K, Maritschnegg E, Valentine CC, Williams LN, Higgins JE, Horvat R, Vanderstichele A, Nachmanson D, Baker KT, Emond MJ, Loter E, Tretiakova M, Soussi T, Loeb LA, Zeillinger R, Speiser P, Risques RA. Salk JJ, et al. Among authors: loubet senear k. Cell Rep. 2019 Jul 2;28(1):132-144.e3. doi: 10.1016/j.celrep.2019.05.109. Cell Rep. 2019. PMID: 31269435 Free PMC article.
Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS).
Nachmanson D, Lian S, Schmidt EK, Hipp MJ, Baker KT, Zhang Y, Tretiakova M, Loubet-Senear K, Kohrn BF, Salk JJ, Kennedy SR, Risques RA. Nachmanson D, et al. Among authors: loubet senear k. Genome Res. 2018 Oct;28(10):1589-1599. doi: 10.1101/gr.235291.118. Epub 2018 Sep 19. Genome Res. 2018. PMID: 30232196 Free PMC article.