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Page 1
Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia.
Cell Stem Cell. 2019 Jul 3;25(1):137-148.e6. doi: 10.1016/j.stem.2019.03.021. Epub 2019 Apr 25.
Cell Stem Cell. 2019.
PMID: 31031138
Free PMC article.
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
Woodley K, Dillingh LS, Giotopoulos G, Madrigal P, Rattigan KM, Philippe C, Dembitz V, Magee AMS, Asby R, van de Lagemaat LN, Mapperley C, James SC, Prehn JHM, Tzelepis K, Rouault-Pierre K, Vassiliou GS, Kranc KR, Helgason GV, Huntly BJP, Gallipoli P.
Woodley K, et al. Among authors: mapperley c.
Nat Commun. 2023 Apr 14;14(1):2132. doi: 10.1038/s41467-023-37652-0.
Nat Commun. 2023.
PMID: 37059720
Free PMC article.
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The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function.
Mapperley C, van de Lagemaat LN, Lawson H, Tavosanis A, Paris J, Campos J, Wotherspoon D, Durko J, Sarapuu A, Choe J, Ivanova I, Krause DS, von Kriegsheim A, Much C, Morgan M, Gregory RI, Mead AJ, O'Carroll D, Kranc KR.
Mapperley C, et al.
J Exp Med. 2021 Mar 1;218(3):e20200829. doi: 10.1084/jem.20200829.
J Exp Med. 2021.
PMID: 33156926
Free PMC article.
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HOXA9 and β-catenin safeguard HSC integrity.
Mapperley C, Kranc KR.
Mapperley C, et al.
Blood. 2024 Apr 18;143(16):1554-1556. doi: 10.1182/blood.2023023755.
Blood. 2024.
PMID: 38635250
No abstract available.
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Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis.
Young C, Russell JR, Van De Lagemaat LN, Lawson H, Mapperley C, Kranc KR, Christophorou MA.
Young C, et al. Among authors: mapperley c.
Biol Open. 2022 Jun 15;11(6):bio059143. doi: 10.1242/bio.059143. Epub 2022 Jun 13.
Biol Open. 2022.
PMID: 35603697
Free PMC article.
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CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation.
Lawson H, van de Lagemaat LN, Barile M, Tavosanis A, Durko J, Villacreces A, Bellani A, Mapperley C, Georges E, Martins-Costa C, Sepulveda C, Allen L, Campos J, Campbell KJ, O'Carroll D, Göttgens B, Cory S, Rodrigues NP, Guitart AV, Kranc KR.
Lawson H, et al. Among authors: mapperley c.
Stem Cell Reports. 2021 Nov 9;16(11):2784-2797. doi: 10.1016/j.stemcr.2021.10.001. Epub 2021 Oct 28.
Stem Cell Reports. 2021.
PMID: 34715054
Free PMC article.
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