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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 3
2006 1
2007 2
2008 3
2009 2
2010 4
2011 2
2012 2
2016 1
2020 1
2023 3
2024 0

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24 results

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Page 1
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors.
Taylor AM, Williams BR, Giordanetto F, Kelley EH, Lescarbeau A, Shortsleeves K, Tang Y, Walters WP, Arrazate A, Bowman C, Brophy E, Chan EW, Deshmukh G, Greisman JB, Hunsaker TL, Kipp DR, Saenz Lopez-Larrocha P, Maddalo D, Martin IJ, Maragakis P, Merchant M, Murcko M, Nisonoff H, Nguyen V, Nguyen V, Orozco O, Owen C, Pierce L, Schmidt M, Shaw DE, Smith S, Therrien E, Tran JC, Watters J, Waters NJ, Wilbur J, Willmore L. Taylor AM, et al. Among authors: maragakis p. J Med Chem. 2023 Oct 12;66(19):13384-13399. doi: 10.1021/acs.jmedchem.3c00483. Epub 2023 Sep 29. J Med Chem. 2023. PMID: 37774359
Gaussian-mixture umbrella sampling.
Maragakis P, van der Vaart A, Karplus M. Maragakis P, et al. J Phys Chem B. 2009 Apr 9;113(14):4664-73. doi: 10.1021/jp808381s. J Phys Chem B. 2009. PMID: 19284746 Free PMC article.
Picosecond to Millisecond Structural Dynamics in Human Ubiquitin.
Lindorff-Larsen K, Maragakis P, Piana S, Shaw DE. Lindorff-Larsen K, et al. Among authors: maragakis p. J Phys Chem B. 2016 Aug 25;120(33):8313-20. doi: 10.1021/acs.jpcb.6b02024. Epub 2016 May 9. J Phys Chem B. 2016. PMID: 27082121 Free article.
Activation mechanism of the β2-adrenergic receptor.
Dror RO, Arlow DH, Maragakis P, Mildorf TJ, Pan AC, Xu H, Borhani DW, Shaw DE. Dror RO, et al. Among authors: maragakis p. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18684-9. doi: 10.1073/pnas.1110499108. Epub 2011 Oct 26. Proc Natl Acad Sci U S A. 2011. PMID: 22031696 Free PMC article.
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography.
Greisman JB, Willmore L, Yeh CY, Giordanetto F, Shahamadtar S, Nisonoff H, Maragakis P, Shaw DE. Greisman JB, et al. Among authors: maragakis p. J Chem Inf Model. 2023 May 8;63(9):2644-2650. doi: 10.1021/acs.jcim.3c00236. Epub 2023 Apr 22. J Chem Inf Model. 2023. PMID: 37086179 Free PMC article.
A differential fluctuation theorem.
Maragakis P, Spichty M, Karplus M. Maragakis P, et al. J Phys Chem B. 2008 May 15;112(19):6168-74. doi: 10.1021/jp077037r. Epub 2008 Mar 11. J Phys Chem B. 2008. PMID: 18331019
Atomic-level characterization of the structural dynamics of proteins.
Shaw DE, Maragakis P, Lindorff-Larsen K, Piana S, Dror RO, Eastwood MP, Bank JA, Jumper JM, Salmon JK, Shan Y, Wriggers W. Shaw DE, et al. Among authors: maragakis p. Science. 2010 Oct 15;330(6002):341-6. doi: 10.1126/science.1187409. Science. 2010. PMID: 20947758
Systematic validation of protein force fields against experimental data.
Lindorff-Larsen K, Maragakis P, Piana S, Eastwood MP, Dror RO, Shaw DE. Lindorff-Larsen K, et al. Among authors: maragakis p. PLoS One. 2012;7(2):e32131. doi: 10.1371/journal.pone.0032131. Epub 2012 Feb 22. PLoS One. 2012. PMID: 22384157 Free PMC article.
24 results