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Page 1
An overview of the safety pharmacology society strategic plan.
Pugsley MK, Authier S, Koerner JE, Redfern WS, Markgraf CG, Brabham T, Correll K, Soloviev MV, Botchway A, Engwall M, Traebert M, Valentin JP, Mow TJ, Greiter-Wilke A, Leishman DJ, Vargas HM. Pugsley MK, et al. Among authors: markgraf cg. J Pharmacol Toxicol Methods. 2018 Sep-Oct;93:35-45. doi: 10.1016/j.vascn.2018.01.001. Epub 2018 Jan 9. J Pharmacol Toxicol Methods. 2018. PMID: 29330132 Review.
The Safety Pharmacology Society salary survey.
Pugsley MK, Authier S, Brabham T, Soloviev M, Markgraf CG, Correll K, Traebert M, Greiter-Wilke A, Valentin JP, Vargas H, Botchway A, Leishman DJ, Curtis MJ. Pugsley MK, et al. Among authors: markgraf cg. J Pharmacol Toxicol Methods. 2017 Nov;88(Pt 1):85-91. doi: 10.1016/j.vascn.2017.08.002. Epub 2017 Aug 7. J Pharmacol Toxicol Methods. 2017. PMID: 28797763
Is there a role for the no observed adverse effect level in safety pharmacology?
Mow T, Andersen NK, Dragsted N, Lassen AB, Laursen M, Bass AS, Valentin JP, Markgraf C, Authier S, Baird TJ, Bhatt S, Traebert M, Leishman DJ, Jones D, Curtis MJ. Mow T, et al. Among authors: markgraf c. J Pharmacol Toxicol Methods. 2020 Sep;105:106917. doi: 10.1016/j.vascn.2020.106917. Epub 2020 Aug 29. J Pharmacol Toxicol Methods. 2020. PMID: 32866658
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates.
Mandal M, Xiao L, Pan W, Scapin G, Li G, Tang H, Yang SW, Pan J, Root Y, de Jesus RK, Yang C, Prosise W, Dayananth P, Mirza A, Therien AG, Young K, Flattery A, Garlisi C, Zhang R, Chu D, Sheth P, Chu I, Wu J, Markgraf C, Kim HY, Painter R, Mayhood TW, DiNunzio E, Wyss DF, Buevich AV, Fischmann T, Pasternak A, Dong S, Hicks JD, Villafania A, Liang L, Murgolo N, Black T, Hagmann WK, Tata J, Parmee ER, Weber AE, Su J, Tang H. Mandal M, et al. Among authors: markgraf c. J Med Chem. 2022 Dec 22;65(24):16234-16251. doi: 10.1021/acs.jmedchem.2c00766. Epub 2022 Dec 7. J Med Chem. 2022. PMID: 36475645
LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits.
Baptista MAS, Merchant K, Barrett T, Bhargava S, Bryce DK, Ellis JM, Estrada AA, Fell MJ, Fiske BK, Fuji RN, Galatsis P, Henry AG, Hill S, Hirst W, Houle C, Kennedy ME, Liu X, Maddess ML, Markgraf C, Mei H, Meier WA, Needle E, Ploch S, Royer C, Rudolph K, Sharma AK, Stepan A, Steyn S, Trost C, Yin Z, Yu H, Wang X, Sherer TB. Baptista MAS, et al. Among authors: markgraf c. Sci Transl Med. 2020 Apr 22;12(540):eaav0820. doi: 10.1126/scitranslmed.aav0820. Sci Transl Med. 2020. PMID: 32321864
Safety pharmacology investigations on the nervous system: An industry survey.
Authier S, Arezzo J, Delatte MS, Kallman MJ, Markgraf C, Paquette D, Pugsley MK, Ratcliffe S, Redfern WS, Stevens J, Valentin JP, Vargas HM, Curtis MJ. Authier S, et al. Among authors: markgraf c. J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:37-46. doi: 10.1016/j.vascn.2016.06.001. Epub 2016 Jun 2. J Pharmacol Toxicol Methods. 2016. PMID: 27263834
39 results