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A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology.
Prabakaran T, Troldborg A, Kumpunya S, Alee I, Marinković E, Windross SJ, Nandakumar R, Narita R, Zhang BC, Carstensen M, Vejvisithsakul P, Marqvorsen MHS, Iversen MB, Holm CK, Østergaard LJ, Pedersen FS, Pisitkun T, Behrendt R, Pisitkun P, Paludan SR. Prabakaran T, et al. Among authors: marqvorsen mhs. EBioMedicine. 2021 Apr;66:103314. doi: 10.1016/j.ebiom.2021.103314. Epub 2021 Apr 2. EBioMedicine. 2021. PMID: 33813142 Free PMC article.
SAM68 directs STING signaling to apoptosis in macrophages.
van der Horst D, Kurmasheva N, Marqvorsen MHS, Assil S, Rahimic AHF, Kollmann CF, Silva da Costa L, Wu Q, Zhao J, Cesari E, Iversen MB, Ren F, Jensen TI, Narita R, Schack VR, Zhang BC, Bak RO, Sette C, Fenton RA, Mikkelsen JG, Paludan SR, Olagnier D. van der Horst D, et al. Among authors: marqvorsen mhs. Commun Biol. 2024 Mar 7;7(1):283. doi: 10.1038/s42003-024-05969-1. Commun Biol. 2024. PMID: 38454028 Free PMC article.
Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands.
van de Graaff MJ, Oosenbrug T, Marqvorsen MHS, Nascimento CR, de Geus MAR, Manoury B, Ressing ME, van Kasteren SI. van de Graaff MJ, et al. Among authors: marqvorsen mhs. Bioconjug Chem. 2020 Jun 17;31(6):1685-1692. doi: 10.1021/acs.bioconjchem.0c00237. Epub 2020 Jun 8. Bioconjug Chem. 2020. PMID: 32510940 Free PMC article.
Bioorthogonal protein labelling enables the study of antigen processing of citrullinated and carbamylated auto-antigens.
van Leeuwen T, Araman C, Pieper Pournara L, Kampstra ASB, Bakkum T, Marqvorsen MHS, Nascimento CR, Groenewold GJM, van der Wulp W, Camps MGM, Janssen GMC, van Veelen PA, van Westen GJP, Janssen APA, Florea BI, Overkleeft HS, Ossendorp FA, Toes REM, van Kasteren SI. van Leeuwen T, et al. Among authors: marqvorsen mhs. RSC Chem Biol. 2021 Feb 23;2(3):855-862. doi: 10.1039/d1cb00009h. RSC Chem Biol. 2021. PMID: 34212151 Free PMC article.
Amyloid-like Behavior of Site-Specifically Citrullinated Myelin Oligodendrocyte Protein (MOG) Peptide Fragments inside EBV-Infected B-Cells Influences Their Cytotoxicity and Autoimmunogenicity.
Araman C, van Gent ME, Meeuwenoord NJ, Heijmans N, Marqvorsen MHS, Doelman W, Faber BW, 't Hart BA, Van Kasteren SI. Araman C, et al. Among authors: marqvorsen mhs. Biochemistry. 2019 Feb 12;58(6):763-775. doi: 10.1021/acs.biochem.8b00852. Epub 2019 Jan 14. Biochemistry. 2019. PMID: 30513201 Free PMC article.
14 results