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Organotropic dendrons with high potency as HIV-1, HIV-2 and EV-A71 cell entry inhibitors.
Martí-Marí O, Martínez-Gualda B, Fernández-Barahona I, Mills A, Abdelnabi R, Noppen S, Neyts J, Schols D, Camarasa MJ, Herranz F, Gago F, San-Félix A. Martí-Marí O, et al. Among authors: martinez gualda b. Eur J Med Chem. 2022 Jul 5;237:114414. doi: 10.1016/j.ejmech.2022.114414. Epub 2022 Apr 27. Eur J Med Chem. 2022. PMID: 35512567 Free article.
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies.
Karim M, Saul S, Ghita L, Sahoo MK, Ye C, Bhalla N, Lo CW, Jin J, Park JG, Martinez-Gualda B, East MP, Johnson GL, Pinsky BA, Martinez-Sobrido L, Asquith CRM, Narayanan A, De Jonghe S, Einav S. Karim M, et al. Among authors: martinez gualda b. Antiviral Res. 2022 Aug;204:105367. doi: 10.1016/j.antiviral.2022.105367. Epub 2022 Jun 20. Antiviral Res. 2022. PMID: 35738348 Free PMC article.
C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
Gargantilla M, Francés C, Adhav A, Forcada-Nadal A, Martínez-Gualda B, Martí-Marí O, López-Redondo ML, Melero R, Marco-Marín C, Gougeard N, Espinosa C, Rubio-Del-Campo A, Ruiz-Partida R, Hernández-Sierra MDP, Villamayor-Belinchón L, Bravo J, Llacer JL, Marina A, Rubio V, San-Félix A, Geller R, Pérez-Pérez MJ. Gargantilla M, et al. Among authors: martinez gualda b. J Med Chem. 2023 Aug 10;66(15):10432-10457. doi: 10.1021/acs.jmedchem.3c00576. Epub 2023 Jul 20. J Med Chem. 2023. PMID: 37471688 Free PMC article.
Galloyl Carbohydrates with Antiangiogenic Activity Mediated by Capillary Morphogenesis Gene 2 (CMG2) Protein Binding.
G-Doyagüez E, Carrero P, Madrona A, Rodriguez-Salamanca P, Martínez-Gualda B, Camarasa MJ, Jimeno ML, Bennallack PR, Finnell JG, Tsang TM, Christensen KA, San-Félix A, Rogers MS. G-Doyagüez E, et al. Among authors: martinez gualda b. J Med Chem. 2019 Apr 25;62(8):3958-3970. doi: 10.1021/acs.jmedchem.8b01988. Epub 2019 Apr 9. J Med Chem. 2019. PMID: 30964669 Free PMC article.
Tryptophan Trimers and Tetramers Inhibit Dengue and Zika Virus Replication by Interfering with Viral Attachment Processes.
Fikatas A, Vervaeke P, Martínez-Gualda B, Martí-Marí O, Noppen S, Meyen E, Camarasa MJ, San-Félix A, Pannecouque C, Schols D. Fikatas A, et al. Among authors: martinez gualda b. Antimicrob Agents Chemother. 2020 Feb 21;64(3):e02130-19. doi: 10.1128/AAC.02130-19. Print 2020 Feb 21. Antimicrob Agents Chemother. 2020. PMID: 31932383 Free PMC article.
Double Arylation of the Indole Side Chain of Tri- and Tetrapodal Tryptophan Derivatives Renders Highly Potent HIV-1 and EV-A71 Entry Inhibitors†.
Martí-Marí O, Martínez-Gualda B, de la Puente-Secades S, Mills A, Quesada E, Abdelnabi R, Sun L, Boonen A, Noppen S, Neyts J, Schols D, Camarasa MJ, Gago F, San-Félix A. Martí-Marí O, et al. Among authors: martinez gualda b. J Med Chem. 2021 Jul 22;64(14):10027-10046. doi: 10.1021/acs.jmedchem.1c00315. Epub 2021 Jul 7. J Med Chem. 2021. PMID: 34229438 Free PMC article.
15 results