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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis.
Matias MI, Yong CS, Foroushani A, Goldsmith C, Mongellaz C, Sezgin E, Levental KR, Talebi A, Perrault J, Rivière A, Dehairs J, Delos O, Bertand-Michel J, Portais JC, Wong M, Marie JC, Kelekar A, Kinet S, Zimmermann VS, Levental I, Yvan-Charvet L, Swinnen JV, Muljo SA, Hernandez-Vargas H, Tardito S, Taylor N, Dardalhon V. Matias MI, et al. Cell Rep. 2021 Nov 2;37(5):109911. doi: 10.1016/j.celrep.2021.109911. Cell Rep. 2021. PMID: 34731632 Free PMC article.
Proteome-wide base editor screens to assess phosphorylation site functionality in high-throughput.
Kennedy PH, Deh Sheikh AA, Balakar M, Jones AC, Olive ME, Hegde M, Matias MI, Pirete N, Burt R, Levy J, Little T, Hogan PG, Liu DR, Doench JG, Newton AC, Gottschalk RA, de Boer C, Alarcón S, Newby G, Myers SA. Kennedy PH, et al. Among authors: matias mi. bioRxiv [Preprint]. 2023 Nov 14:2023.11.11.566649. doi: 10.1101/2023.11.11.566649. bioRxiv. 2023. PMID: 38014346 Free PMC article. Preprint.
Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation.
Klysz D, Tai X, Robert PA, Craveiro M, Cretenet G, Oburoglu L, Mongellaz C, Floess S, Fritz V, Matias MI, Yong C, Surh N, Marie JC, Huehn J, Zimmermann V, Kinet S, Dardalhon V, Taylor N. Klysz D, et al. Among authors: matias mi. Sci Signal. 2015 Sep 29;8(396):ra97. doi: 10.1126/scisignal.aab2610. Sci Signal. 2015. PMID: 26420908