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Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death.
Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO. Bright SJ, et al. Among authors: mcfadden ch. Int J Radiat Oncol Biol Phys. 2019 Dec 1;105(5):1119-1125. doi: 10.1016/j.ijrobp.2019.08.011. Epub 2019 Aug 16. Int J Radiat Oncol Biol Phys. 2019. PMID: 31425731 Free PMC article.
Cell lines of the same anatomic site and histologic type show large variability in intrinsic radiosensitivity and relative biological effectiveness to protons and carbon ions.
Flint DB, Bright SJ, McFadden CH, Konishi T, Ohsawa D, Turner B, Lin SH, Grosshans DR, Chiu HS, Sumazin P, Shaitelman SF, Sawakuchi GO. Flint DB, et al. Among authors: mcfadden ch. Med Phys. 2021 Jun;48(6):3243-3261. doi: 10.1002/mp.14878. Epub 2021 May 9. Med Phys. 2021. PMID: 33837540