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Page 1
BacPROTACs mediate targeted protein degradation in bacteria.
Cell. 2022 Jun 23;185(13):2338-2353.e18. doi: 10.1016/j.cell.2022.05.009. Epub 2022 Jun 3.
Cell. 2022.
PMID: 35662409
Free PMC article.
Types of Ubiquitin Ligases.
Morreale FE, Walden H.
Morreale FE, et al.
Cell. 2016 Mar 24;165(1):248-248.e1. doi: 10.1016/j.cell.2016.03.003.
Cell. 2016.
PMID: 27015313
Free article.
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Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Hoi DM, Junker S, Junk L, Schwechel K, Fischel K, Podlesainski D, Hawkins PME, van Geelen L, Kaschani F, Leodolter J, Morreale FE, Kleine S, Guha S, Rumpel K, Schmiedel VM, Weinstabl H, Meinhart A, Payne RJ, Kaiser M, Hartl M, Boehmelt G, Kazmaier U, Kalscheuer R, Clausen T.
Hoi DM, et al. Among authors: morreale fe.
Cell. 2023 May 11;186(10):2176-2192.e22. doi: 10.1016/j.cell.2023.04.009. Epub 2023 May 2.
Cell. 2023.
PMID: 37137307
Free article.
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Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria.
Junk L, Schmiedel VM, Guha S, Fischel K, Greb P, Vill K, Krisilia V, van Geelen L, Rumpel K, Kaur P, Krishnamurthy RV, Narayanan S, Shandil RK, Singh M, Kofink C, Mantoulidis A, Biber P, Gmaschitz G, Kazmaier U, Meinhart A, Leodolter J, Hoi D, Junker S, Morreale FE, Clausen T, Kalscheuer R, Weinstabl H, Boehmelt G.
Junk L, et al. Among authors: morreale fe.
Nat Commun. 2024 Mar 5;15(1):2005. doi: 10.1038/s41467-024-46218-7.
Nat Commun. 2024.
PMID: 38443338
Free PMC article.
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Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening.
Morreale FE, Bortoluzzi A, Chaugule VK, Arkinson C, Walden H, Ciulli A.
Morreale FE, et al.
J Med Chem. 2017 May 11;60(9):4093-4098. doi: 10.1021/acs.jmedchem.7b00147. Epub 2017 May 2.
J Med Chem. 2017.
PMID: 28437106
Free PMC article.
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Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.
Morreale FE, Testa A, Chaugule VK, Bortoluzzi A, Ciulli A, Walden H.
Morreale FE, et al.
J Med Chem. 2017 Oct 12;60(19):8183-8191. doi: 10.1021/acs.jmedchem.7b01071. Epub 2017 Oct 3.
J Med Chem. 2017.
PMID: 28933844
Free PMC article.
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