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A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.
Proc Natl Acad Sci U S A. 2024 Jan 23;121(4):e2318093121. doi: 10.1073/pnas.2318093121. Epub 2024 Jan 17.
Proc Natl Acad Sci U S A. 2024.
PMID: 38232291
Free PMC article.
The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest.
Moustafa-Kamal M, Kucharski TJ, El-Assaad W, Abbas YM, Gandin V, Nagar B, Pelletier J, Topisirovic I, Teodoro JG.
Moustafa-Kamal M, et al.
Cell Rep. 2020 Oct 6;33(1):108230. doi: 10.1016/j.celrep.2020.108230.
Cell Rep. 2020.
PMID: 33027666
Free article.
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Germline Missense Variants in CDC20 Result in Aberrant Mitotic Progression and Familial Cancer.
Chen OJ, Castellsagué E, Moustafa-Kamal M, Nadaf J, Rivera B, Fahiminiya S, Wang Y, Gamache I, Pacifico C, Jiang L, Carrot-Zhang J, Witkowski L, Berghuis AM, Schönberger S, Schneider D, Hillmer M, Bens S, Siebert R, Stewart CJR, Zhang Z, Chao WCH, Greenwood CMT, Barford D, Tischkowitz M, Majewski J, Foulkes WD, Teodoro JG.
Chen OJ, et al. Among authors: moustafa kamal m.
Cancer Res. 2022 Oct 4;82(19):3499-3515. doi: 10.1158/0008-5472.CAN-21-3956.
Cancer Res. 2022.
PMID: 35913887
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BimEL is phosphorylated at mitosis by Aurora A and targeted for degradation by βTrCP1.
Moustafa-Kamal M, Gamache I, Lu Y, Li S, Teodoro JG.
Moustafa-Kamal M, et al.
Cell Death Differ. 2013 Oct;20(10):1393-403. doi: 10.1038/cdd.2013.93. Epub 2013 Aug 2.
Cell Death Differ. 2013.
PMID: 23912711
Free PMC article.
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Reciprocal Regulation between 53BP1 and the Anaphase-Promoting Complex/Cyclosome Is Required for Genomic Stability during Mitotic Stress.
Kucharski TJ, Minshall PE, Moustafa-Kamal M, Turnell AS, Teodoro JG.
Kucharski TJ, et al. Among authors: moustafa kamal m.
Cell Rep. 2017 Feb 21;18(8):1982-1995. doi: 10.1016/j.celrep.2017.01.080.
Cell Rep. 2017.
PMID: 28228263
Free article.
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