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Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin.
Kim H, Leng K, Park J, Sorets AG, Kim S, Shostak A, Embalabala RJ, Mlouk K, Katdare KA, Rose IVL, Sturgeon SM, Neal EH, Ao Y, Wang S, Sofroniew MV, Brunger JM, McMahon DG, Schrag MS, Kampmann M, Lippmann ES. Kim H, et al. Among authors: neal eh. Nat Commun. 2022 Nov 2;13(1):6581. doi: 10.1038/s41467-022-34412-4. Nat Commun. 2022. PMID: 36323693 Free PMC article.
IQGAP2 regulates blood-brain barrier immune dynamics.
Katdare KA, Kjar A, O'Brown NM, Neal EH, Sorets AG, Shostak A, Romero-Fernandez W, Kwiatkowski AJ, Mlouk K, Kim H, Cowell RP, Schwensen KR, Horner KB, Wilson JT, Schrag MS, Megason SG, Lippmann ES. Katdare KA, et al. Among authors: neal eh. bioRxiv [Preprint]. 2024 Apr 12:2023.02.07.527394. doi: 10.1101/2023.02.07.527394. bioRxiv. 2024. PMID: 38645082 Free PMC article. Preprint.