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Chromosome errors in human eggs shape natural fertility over reproductive life span.
Gruhn JR, Zielinska AP, Shukla V, Blanshard R, Capalbo A, Cimadomo D, Nikiforov D, Chan AC, Newnham LJ, Vogel I, Scarica C, Krapchev M, Taylor D, Kristensen SG, Cheng J, Ernst E, Bjørn AB, Colmorn LB, Blayney M, Elder K, Liss J, Hartshorne G, Grøndahl ML, Rienzi L, Ubaldi F, McCoy R, Lukaszuk K, Andersen CY, Schuh M, Hoffmann ER. Gruhn JR, et al. Among authors: newnham lj. Science. 2019 Sep 27;365(6460):1466-1469. doi: 10.1126/science.aav7321. Science. 2019. PMID: 31604276 Free PMC article.
Tripolar chromosome segregation drives the association between maternal genotype at variants spanning PLK4 and aneuploidy in human preimplantation embryos.
McCoy RC, Newnham LJ, Ottolini CS, Hoffmann ER, Chatzimeletiou K, Cornejo OE, Zhan Q, Zaninovic N, Rosenwaks Z, Petrov DA, Demko ZP, Sigurjonsson S, Handyside AH. McCoy RC, et al. Among authors: newnham lj. Hum Mol Genet. 2018 Jul 15;27(14):2573-2585. doi: 10.1093/hmg/ddy147. Hum Mol Genet. 2018. PMID: 29688390 Free PMC article.