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The self-peptide repertoire plays a critical role in transplant tolerance induction.
Son ET, Faridi P, Paul-Heng M, Leong ML, English K, Ramarathinam SH, Braun A, Dudek NL, Alexander IE, Lisowski L, Bertolino P, Bowen DG, Purcell AW, Mifsud NA, Sharland AF. Son ET, et al. Among authors: paul heng m. J Clin Invest. 2021 Nov 1;131(21):e146771. doi: 10.1172/JCI146771. J Clin Invest. 2021. PMID: 34428180 Free PMC article.
Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction.
Paul-Heng M, Leong M, Cunningham E, Bunker DLJ, Bremner K, Wang Z, Wang C, Tay SS, McGuffog C, Logan GJ, Alexander IE, Hu M, Alexander SI, Sparwasser TD, Bertolino P, Bowen DG, Bishop GA, Sharland A. Paul-Heng M, et al. JCI Insight. 2018 Aug 9;3(15):e97500. doi: 10.1172/jci.insight.97500. eCollection 2018 Aug 9. JCI Insight. 2018. PMID: 30089715 Free PMC article.