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Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth.
Cell Chem Biol. 2023 Dec 5:S2451-9456(23)00421-X. doi: 10.1016/j.chembiol.2023.11.006. Online ahead of print.
Cell Chem Biol. 2023.
PMID: 38056465
A comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies.
Hoberecht L, Perampalam P, Lun A, Fortin JP.
Hoberecht L, et al. Among authors: perampalam p.
Nat Commun. 2022 Nov 2;13(1):6568. doi: 10.1038/s41467-022-34320-7.
Nat Commun. 2022.
PMID: 36323688
Free PMC article.
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Disrupting the DREAM transcriptional repressor complex induces apolipoprotein overexpression and systemic amyloidosis in mice.
Perampalam P, Hassan HM, Lilly GE, Passos DT, Torchia J, Kiser PK, Bozovic A, Kulasingam V, Dick FA.
Perampalam P, et al.
J Clin Invest. 2021 Feb 15;131(4):e140903. doi: 10.1172/JCI140903.
J Clin Invest. 2021.
PMID: 33444292
Free PMC article.
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BEAVR: a browser-based tool for the exploration and visualization of RNA-seq data.
Perampalam P, Dick FA.
Perampalam P, et al.
BMC Bioinformatics. 2020 May 29;21(1):221. doi: 10.1186/s12859-020-03549-8.
BMC Bioinformatics. 2020.
PMID: 32471392
Free PMC article.
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A Systematic Analysis of Negative Growth Control Implicates the DREAM Complex in Cancer Cell Dormancy.
MacDonald J, Ramos-Valdes Y, Perampalam P, Litovchick L, DiMattia GE, Dick FA.
MacDonald J, et al. Among authors: perampalam p.
Mol Cancer Res. 2017 Apr;15(4):371-381. doi: 10.1158/1541-7786.MCR-16-0323-T. Epub 2016 Dec 28.
Mol Cancer Res. 2017.
PMID: 28031411
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