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1986 1
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Page 1
Discovery and Characterization of Novel CNS-Penetrant GPR55 Agonists.
Hewer RC, Christie LA, Doyle KJ, Xu X, Roberts MJ, Dickson L, Cheung T, Cadwalladr DH, Pickford P, Teall M, Powell JAC, Sheardown S, Narayana L, Brice NL, Dawson LA, Carlton M, Bürli RW. Hewer RC, et al. Among authors: pickford p. J Med Chem. 2023 Sep 28;66(18):12858-12876. doi: 10.1021/acs.jmedchem.3c00784. Epub 2023 Sep 14. J Med Chem. 2023. PMID: 37708305
Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors.
Jones B, McGlone ER, Fang Z, Pickford P, Corrêa IR Jr, Oishi A, Jockers R, Inoue A, Kumar S, Görlitz F, Dunsby C, French PMW, Rutter GA, Tan T, Tomas A, Bloom SR. Jones B, et al. Among authors: pickford p. J Biol Chem. 2021 Jan-Jun;296:100133. doi: 10.1074/jbc.RA120.016334. Epub 2020 Dec 4. J Biol Chem. 2021. PMID: 33268378 Free PMC article.
The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists.
Fang Z, Chen S, Pickford P, Broichhagen J, Hodson DJ, Corrêa IR Jr, Kumar S, Görlitz F, Dunsby C, French PMW, Rutter GA, Tan T, Bloom SR, Tomas A, Jones B. Fang Z, et al. Among authors: pickford p. ACS Pharmacol Transl Sci. 2020 Mar 17;3(2):345-360. doi: 10.1021/acsptsci.0c00022. eCollection 2020 Apr 10. ACS Pharmacol Transl Sci. 2020. PMID: 32296773 Free PMC article.
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells.
Fang Z, Chen S, Manchanda Y, Bitsi S, Pickford P, David A, Shchepinova MM, Corrêa IR Jr, Hodson DJ, Broichhagen J, Tate EW, Reimann F, Salem V, Rutter GA, Tan T, Bloom SR, Tomas A, Jones B. Fang Z, et al. Among authors: pickford p. Int J Mol Sci. 2020 Nov 9;21(21):8404. doi: 10.3390/ijms21218404. Int J Mol Sci. 2020. PMID: 33182425 Free PMC article.
12 results