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Mitochondrial ubiquinol oxidation is necessary for tumour growth.
Martínez-Reyes I, Cardona LR, Kong H, Vasan K, McElroy GS, Werner M, Kihshen H, Reczek CR, Weinberg SE, Gao P, Steinert EM, Piseaux R, Budinger GRS, Chandel NS. Martínez-Reyes I, et al. Among authors: piseaux r. Nature. 2020 Sep;585(7824):288-292. doi: 10.1038/s41586-020-2475-6. Epub 2020 Jul 8. Nature. 2020. PMID: 32641834 Free PMC article.
Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage.
Kim SJ, Cheresh P, Jablonski RP, Morales-Nebreda L, Cheng Y, Hogan E, Yeldandi A, Chi M, Piseaux R, Ridge K, Michael Hart C, Chandel N, Scott Budinger GR, Kamp DW. Kim SJ, et al. Among authors: piseaux r. Free Radic Biol Med. 2016 Dec;101:482-490. doi: 10.1016/j.freeradbiomed.2016.11.007. Epub 2016 Nov 11. Free Radic Biol Med. 2016. PMID: 27840320 Free PMC article.