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Structure-Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands.
Fronik P, Poetsch I, Kastner A, Mendrina T, Hager S, Hohenwallner K, Schueffl H, Herndler-Brandstetter D, Koellensperger G, Rampler E, Kopecka J, Riganti C, Berger W, Keppler BK, Heffeter P, Kowol CR. Fronik P, et al. Among authors: poetsch i. J Med Chem. 2021 Aug 26;64(16):12132-12151. doi: 10.1021/acs.jmedchem.1c00770. Epub 2021 Aug 17. J Med Chem. 2021. PMID: 34403254 Free PMC article.
Detection of oxaliplatin- and cisplatin-DNA lesions requires different global genome repair mechanisms that affect their clinical efficacy.
Slyskova J, Muniesa-Vargas A, da Silva IT, Drummond R, Park J, Häckes D, Poetsch I, Ribeiro-Silva C, Moretton A, Heffeter P, Schärer OD, Vermeulen W, Lans H, Loizou JI. Slyskova J, et al. Among authors: poetsch i. NAR Cancer. 2023 Dec 5;5(4):zcad057. doi: 10.1093/narcan/zcad057. eCollection 2023 Dec. NAR Cancer. 2023. PMID: 38058548 Free PMC article.