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Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial.
Geroscience. 2019 Dec;41(6):861-869. doi: 10.1007/s11357-019-00113-y. Epub 2019 Nov 25.
Geroscience. 2019.
PMID: 31761958
Free PMC article.
Clinical Trial.
The methyltransferase enzymes KMT2D, SETD1B, and ASH1L are key mediators of both metabolic and epigenetic changes during cellular senescence.
Nacarelli T, Azar A, Potnis M, Johannes G, Mell J, Johnson FB, Brown-Borg H, Noguchi E, Sell C.
Nacarelli T, et al. Among authors: potnis m.
Mol Biol Cell. 2022 May 1;33(5):ar36. doi: 10.1091/mbc.E20-08-0523. Epub 2022 Feb 23.
Mol Biol Cell. 2022.
PMID: 35196069
Free PMC article.
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