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Page 1
MEN1 mutations mediate clinical resistance to menin inhibition.
Nature. 2023 Mar;615(7954):913-919. doi: 10.1038/s41586-023-05755-9. Epub 2023 Mar 15.
Nature. 2023.
PMID: 36922589
Free PMC article.
Clinical Trial.
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia.
Aubrey BJ, Cutler JA, Bourgeois W, Donovan KA, Gu S, Hatton C, Perlee S, Perner F, Rahnamoun H, Theall ACP, Henrich JA, Zhu Q, Nowak RP, Kim YJ, Parvin S, Cremer A, Olsen SN, Eleuteri NA, Pikman Y, McGeehan GM, Stegmaier K, Letai A, Fischer ES, Liu XS, Armstrong SA.
Aubrey BJ, et al. Among authors: rahnamoun h.
Nat Cancer. 2022 May;3(5):595-613. doi: 10.1038/s43018-022-00366-1. Epub 2022 May 9.
Nat Cancer. 2022.
PMID: 35534777
Free PMC article.
Item in Clipboard
The role of enhancer RNAs in epigenetic regulation of gene expression.
Rahnamoun H, Orozco P, Lauberth SM.
Rahnamoun H, et al.
Transcription. 2020 Feb;11(1):19-25. doi: 10.1080/21541264.2019.1698934. Epub 2019 Dec 11.
Transcription. 2020.
PMID: 31823686
Free PMC article.
Review.
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RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation.
Rahnamoun H, Lee J, Sun Z, Lu H, Ramsey KM, Komives EA, Lauberth SM.
Rahnamoun H, et al.
Nat Struct Mol Biol. 2018 Aug;25(8):687-697. doi: 10.1038/s41594-018-0102-0. Epub 2018 Aug 3.
Nat Struct Mol Biol. 2018.
PMID: 30076409
Free PMC article.
Item in Clipboard
Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.
Rahnamoun H, Hong J, Sun Z, Lee J, Lu H, Lauberth SM.
Rahnamoun H, et al.
J Biol Chem. 2018 Aug 24;293(34):13234-13246. doi: 10.1074/jbc.RA118.003387. Epub 2018 Jun 28.
J Biol Chem. 2018.
PMID: 29954944
Free PMC article.
Item in Clipboard
Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling.
Rahnamoun H, Lu H, Duttke SH, Benner C, Glass CK, Lauberth SM.
Rahnamoun H, et al.
Nat Commun. 2017 Sep 29;8(1):754. doi: 10.1038/s41467-017-01117-y.
Nat Commun. 2017.
PMID: 28963538
Free PMC article.
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The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output.
Stijf-Bultsma Y, Sommer L, Tauber M, Baalbaki M, Giardoglou P, Jones DR, Gelato KA, van Pelt J, Shah Z, Rahnamoun H, Toma C, Anderson KE, Hawkins P, Lauberth SM, Haramis AP, Hart D, Fischle W, Divecha N.
Stijf-Bultsma Y, et al. Among authors: rahnamoun h.
Mol Cell. 2015 May 7;58(3):453-67. doi: 10.1016/j.molcel.2015.03.009. Epub 2015 Apr 9.
Mol Cell. 2015.
PMID: 25866244
Free PMC article.
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