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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2005 2
2006 2
2007 3
2008 3
2009 3
2010 3
2013 1
2014 5
2015 1
2016 2
2017 3
2018 3
2019 2
2020 3
2021 3
2022 3
2023 2
2024 2

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41 results

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Page 1
Hit-to-Lead: Hit Validation and Assessment.
Hevener KE, Pesavento R, Ren J, Lee H, Ratia K, Johnson ME. Hevener KE, et al. Among authors: ratia k. Methods Enzymol. 2018;610:265-309. doi: 10.1016/bs.mie.2018.09.022. Epub 2018 Oct 25. Methods Enzymol. 2018. PMID: 30390802
Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors.
Lazzara PR, Jain AD, Maldonado AC, Richardson B, Skowron KJ, David BP, Siddiqui Z, Ratia KM, Moore TW. Lazzara PR, et al. Among authors: ratia km. ACS Med Chem Lett. 2020 Feb 19;11(4):521-527. doi: 10.1021/acsmedchemlett.9b00631. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292559 Free PMC article.
Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs).
Shen Z, Ratia K, Krider I, Ackerman-Berrier M, Penton C, Musku SR, Gordon-Blake JM, Laham MS, Christie N, Ma N, Fu J, Xiong R, Courey JM, Velma GR, Thatcher GRJ. Shen Z, et al. Among authors: ratia k. J Med Chem. 2023 Dec 28;66(24):16704-16727. doi: 10.1021/acs.jmedchem.3c01406. Epub 2023 Dec 14. J Med Chem. 2023. PMID: 38096366 Free article.
XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer.
Principe DR, Xiong R, Li Y, Pham TND, Kamath SD, Dubrovskyi O, Ratia K, Huang F, Zhao J, Shen Z, Thummuri D, Daohong Z, Underwood PW, Trevino J, Munshi HG, Thatcher GRJ, Rana A. Principe DR, et al. Among authors: ratia k. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2116764119. doi: 10.1073/pnas.2116764119. Proc Natl Acad Sci U S A. 2022. PMID: 35064087 Free PMC article.
PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer.
Salvi A, Young AN, Huntsman AC, Pergande MR, Korkmaz MA, Rathnayake RA, Mize BK, Kinghorn AD, Zhang X, Ratia K, Schirle M, Thomas JR, Brittain SM, Shelton C, Aldrich LN, Cologna SM, Fuchs JR, Burdette JE. Salvi A, et al. Among authors: ratia k. Cell Death Dis. 2022 Jan 10;13(1):45. doi: 10.1038/s41419-021-04495-w. Cell Death Dis. 2022. PMID: 35013112 Free PMC article.
41 results