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Page 1
Conformational inhibitors of protein aggregation.
Fernández Ramírez MDC, Afrin S, Saelices L. Fernández Ramírez MDC, et al. Among authors: saelices l. Curr Opin Struct Biol. 2023 Dec;83:102700. doi: 10.1016/j.sbi.2023.102700. Epub 2023 Sep 15. Curr Opin Struct Biol. 2023. PMID: 37717490 Review.
Update on Disease-Specific Biomarkers in Transthyretin Cardiac Amyloidosis.
Hood CJ, Hendren NS, Pedretti R, Roth LR, Saelices L, Grodin JL. Hood CJ, et al. Among authors: saelices l. Curr Heart Fail Rep. 2022 Oct;19(5):356-363. doi: 10.1007/s11897-022-00570-1. Epub 2022 Aug 5. Curr Heart Fail Rep. 2022. PMID: 35930129 Free PMC article. Review.
O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology.
Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR. Balana AT, et al. Among authors: saelices l. bioRxiv [Preprint]. 2023 Mar 7:2023.03.07.531573. doi: 10.1101/2023.03.07.531573. bioRxiv. 2023. PMID: 36945566 Free PMC article. Updated. Preprint.
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: saelices l. Nat Commun. 2023 Apr 25;14(1):2379. doi: 10.1038/s41467-023-37865-3. Nat Commun. 2023. PMID: 37185252 Free PMC article.
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pękała M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L. Nguyen BA, et al. Among authors: saelices l. Nat Commun. 2024 Jan 17;15(1):581. doi: 10.1038/s41467-024-44820-3. Nat Commun. 2024. PMID: 38233397 Free PMC article.
Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Tayeb-Fligelman E, Cheng X, Tai C, Bowler JT, Griner S, Sawaya MR, Seidler PM, Jiang YX, Lu J, Rosenberg GM, Salwinski L, Abskharon R, Zee CT, Hou K, Li Y, Boyer DR, Murray KA, Falcon G, Anderson DH, Cascio D, Saelices L, Damoiseaux R, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: saelices l. bioRxiv [Preprint]. 2021 Mar 18:2021.03.05.434000. doi: 10.1101/2021.03.05.434000. bioRxiv. 2021. PMID: 33688654 Free PMC article. Preprint.
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