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Page 1
In vivo prime editing of a metabolic liver disease in mice.
Sci Transl Med. 2022 Mar 16;14(636):eabl9238. doi: 10.1126/scitranslmed.abl9238. Epub 2022 Mar 16.
Sci Transl Med. 2022.
PMID: 35294257
Free PMC article.
Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.
Schmidheini L, Mathis N, Marquart KF, Rothgangl T, Kissling L, Böck D, Chanez C, Wang JP, Jinek M, Schwank G.
Schmidheini L, et al.
Nat Chem Biol. 2024 Mar;20(3):333-343. doi: 10.1038/s41589-023-01427-x. Epub 2023 Sep 21.
Nat Chem Biol. 2024.
PMID: 37735239
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Self-Assembly of Nanodiamonds and Plasmonic Nanoparticles for Nanoscopy.
Schmidheini L, Tiefenauer RF, Gatterdam V, Frutiger A, Sannomiya T, Aramesh M.
Schmidheini L, et al.
Biosensors (Basel). 2022 Feb 28;12(3):148. doi: 10.3390/bios12030148.
Biosensors (Basel). 2022.
PMID: 35323419
Free PMC article.
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Predicting prime editing efficiency and product purity by deep learning.
Mathis N, Allam A, Kissling L, Marquart KF, Schmidheini L, Solari C, Balázs Z, Krauthammer M, Schwank G.
Mathis N, et al. Among authors: schmidheini l.
Nat Biotechnol. 2023 Aug;41(8):1151-1159. doi: 10.1038/s41587-022-01613-7. Epub 2023 Jan 16.
Nat Biotechnol. 2023.
PMID: 36646933
Free PMC article.
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Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.
Villiger L, Schmidheini L, Mathis N, Rothgangl T, Marquart K, Schwank G.
Villiger L, et al. Among authors: schmidheini l.
Mol Ther Nucleic Acids. 2021 Aug 26;26:502-510. doi: 10.1016/j.omtn.2021.08.025. eCollection 2021 Dec 3.
Mol Ther Nucleic Acids. 2021.
PMID: 34631280
Free PMC article.
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Dark-Field Microwells toward High-Throughput Direct miRNA Sensing with Gold Nanoparticles.
Hwu S, Blickenstorfer Y, Tiefenauer RF, Gonnelli C, Schmidheini L, Lüchtefeld I, Hoogenberg BJ, Gisiger AB, Vörös J.
Hwu S, et al. Among authors: schmidheini l.
ACS Sens. 2019 Jul 26;4(7):1950-1956. doi: 10.1021/acssensors.9b00946. Epub 2019 Jul 16.
ACS Sens. 2019.
PMID: 31310098
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