Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Affiliations

• ¹ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. p.wainschtein@uq.edu.au.
• ² Department of Biostatistics, University of Washington, Seattle, WA, USA.
• ³ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
• ⁴ Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
• ⁵ Framingham Heart Study, Framingham, MA, USA.
• ⁶ Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA.
• ⁷ Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
• ⁸ Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
• ⁹ Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA.
• ¹⁰ Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
• ¹¹ Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
• ¹² Harvard Medical School, Boston, MA, USA.
• ¹³ Division of Cardiovascular, Brigham and Women's Hospital, Boston, MA, USA.
• ¹⁴ Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
• ¹⁵ Departments of Medicine, Pharmacology and Bioinformatics, Vanderbilt University Medical Center, Nashville, TN, USA.
• ¹⁶ Department of Medicine, University of Illinois-Chicago, Chicago, IL, USA.
• ¹⁷ Department of Preventive Medicine, Northwestern University, Chicago, IL, USA.
• ¹⁸ Dean's Office, College of Public Health, University of Kentucky, Lexington, KY, USA.
• ¹⁹ Department of Medicine, National Jewish Health, Denver, CO, USA.
• ²⁰ Health Science Center, University of Texas, Houston, TX, USA.
• ²¹ Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
• ²² Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
• ²³ Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
• ²⁴ Department of Family Medicine, University of California San Diego, La Jolla, CA, USA.
• ²⁵ Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
• ²⁶ Department of Molecular Cardiology, Cleveland Clinic, Cleveland, OH, USA.
• ²⁷ Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
• ²⁸ Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
• ²⁹ Mindich Institute for Child Health and Development, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
• ³⁰ Cardiovascular Health Research Unit and Department of Epidemiology, University of Washington, Seattle, WA, USA.
• ³¹ Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
• ³² Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, WA, USA.
• ³³ Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA, USA.
• ³⁴ Sections of Preventive Medicine and Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
• ³⁵ Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
• ³⁶ GeneSTAR Research Program, Divisions of Allergy and Clinical Immunology and General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
• ³⁷ Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
• ³⁸ Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
• ³⁹ Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
• ⁴⁰ Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.
• ⁴¹ Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
• ⁴² Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.
• ⁴³ Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
• ⁴⁴ International Health Institute, Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
• ⁴⁵ Centre for AgriBioscience, Department of Economic Development, Jobs, Transport and Resources, Bundoora, Victoria, Australia.
• ⁴⁶ Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia.
• ⁴⁷ Department of Epidemiology and Carolina Center of Genome Sciences, University of North Carolina, Chapel Hill, NC, USA.
• ⁴⁸ Department of Medicine, University of Colorado, Aurora, CO, USA.
• ⁴⁹ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. jian.yang@westlake.edu.cn.
• ⁵⁰ School of Life Sciences, Westlake University, Hangzhou Zhejiang, China. jian.yang@westlake.edu.cn.
• ⁵¹ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. peter.visscher@uq.edu.au.
• ⁵² Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. peter.visscher@uq.edu.au.