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Adhesion-mediated mechanosignaling forces mitohormesis.
Tharp KM, Higuchi-Sanabria R, Timblin GA, Ford B, Garzon-Coral C, Schneider C, Muncie JM, Stashko C, Daniele JR, Moore AS, Frankino PA, Homentcovschi S, Manoli SS, Shao H, Richards AL, Chen KH, Hoeve JT, Ku GM, Hellerstein M, Nomura DK, Saijo K, Gestwicki J, Dunn AR, Krogan NJ, Swaney DL, Dillin A, Weaver VM. Tharp KM, et al. Among authors: stashko c. Cell Metab. 2021 Jul 6;33(7):1322-1341.e13. doi: 10.1016/j.cmet.2021.04.017. Epub 2021 May 20. Cell Metab. 2021. PMID: 34019840 Free PMC article.
Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix.
Jiang H, Torphy RJ, Steiger K, Hongo H, Ritchie AJ, Kriegsmann M, Horst D, Umetsu SE, Joseph NM, McGregor K, Pishvaian MJ, Blais EM, Lu B, Li M, Hollingsworth M, Stashko C, Volmar K, Yeh JJ, Weaver VM, Wang ZJ, Tempero MA, Weichert W, Collisson EA. Jiang H, et al. Among authors: stashko c. J Clin Invest. 2020 Sep 1;130(9):4704-4709. doi: 10.1172/JCI136760. J Clin Invest. 2020. PMID: 32749238 Free PMC article.
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells.
Kai F, Ou G, Tourdot RW, Stashko C, Gaietta G, Swift MF, Volkmann N, Long AF, Han Y, Huang HH, Northey JJ, Leidal AM, Viasnoff V, Bryant DM, Guo W, Wiita AP, Guo M, Dumont S, Hanein D, Radhakrishnan R, Weaver VM. Kai F, et al. Among authors: stashko c. EMBO J. 2022 Sep 1;41(17):e109205. doi: 10.15252/embj.2021109205. Epub 2022 Jul 25. EMBO J. 2022. PMID: 35880301 Free PMC article.