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Multiplexed single-cell analysis reveals prognostic and nonprognostic T cell types in human colorectal cancer.
Masuda K, Kornberg A, Miller J, Lin S, Suek N, Botella T, Secener KA, Bacarella AM, Cheng L, Ingham M, Rosario V, Al-Mazrou AM, Lee-Kong SA, Kiran RP, Stoeckius M, Smibert P, Del Portillo A, Oberstein PE, Sims PA, Yan KS, Han A. Masuda K, et al. Among authors: suek n. JCI Insight. 2022 Apr 8;7(7):e154646. doi: 10.1172/jci.insight.154646. JCI Insight. 2022. PMID: 35192548 Free PMC article.
Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade.
Ghosh A, Michels J, Mezzadra R, Venkatesh D, Dong L, Gomez R, Samaan F, Ho YJ, Campesato LF, Mangarin L, Fak J, Suek N, Holland A, Liu C, Abu-Akeel M, Bykov Y, Zhong H, Fitzgerald K, Budhu S, Chow A, Zappasodi R, Panageas KS, de Henau O, Ruscetti M, Lowe SW, Merghoub T, Wolchok JD. Ghosh A, et al. Among authors: suek n. J Clin Invest. 2022 Sep 15;132(18):e148141. doi: 10.1172/JCI148141. J Clin Invest. 2022. PMID: 36106631 Free PMC article.
In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors.
Khalil DN, Suek N, Campesato LF, Budhu S, Redmond D, Samstein RM, Krishna C, Panageas KS, Capanu M, Houghton S, Hirschhorn D, Zappasodi R, Giese R, Gasmi B, Schneider M, Gupta A, Harding JJ, Moral JA, Balachandran VP, Wolchok JD, Merghoub T. Khalil DN, et al. Among authors: suek n. J Clin Invest. 2019 Jul 22;129(8):3435-3447. doi: 10.1172/JCI128562. eCollection 2019 Jul 22. J Clin Invest. 2019. PMID: 31329159 Free PMC article.