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Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence.
Dahl HC, Kanchwala M, Thomas-Jardin SE, Sandhu A, Kanumuri P, Nawas AF, Xing C, Lin C, Frigo DE, Delk NA. Dahl HC, et al. Among authors: thomas jardin se. PLoS One. 2020 Dec 16;15(12):e0242970. doi: 10.1371/journal.pone.0242970. eCollection 2020. PLoS One. 2020. PMID: 33326447 Free PMC article.
IL-1 induces p62/SQSTM1 and autophagy in ERα+ /PR+ BCa cell lines concomitant with ERα and PR repression, conferring an ERα- /PR- BCa-like phenotype.
Nawas AF, Mistry R, Narayanan S, Thomas-Jardin SE, Ramachandran J, Ravichandran J, Neduvelil E, Luangpanh K, Delk NA. Nawas AF, et al. Among authors: thomas jardin se. J Cell Biochem. 2019 Feb;120(2):1477-1491. doi: 10.1002/jcb.27340. Epub 2018 Oct 15. J Cell Biochem. 2019. PMID: 30324661 Free PMC article.