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Page 1
The Singapore National Precision Medicine Strategy.
Wong E, Bertin N, Hebrard M, Tirado-Magallanes R, Bellis C, Lim WK, Chua CY, Tong PML, Chua R, Mak K, Lim TM, Cheong WY, Thien KE, Goh KT, Chai JF, Lee J, Sung JJ, Wong TY, Chin CWL, Gluckman PD, Goh LL, Ban KHK, Tan TW; SG10K_Health Consortium; Sim X, Cheng CY, Davila S, Karnani N, Leong KP, Liu J, Prabhakar S, Maurer-Stroh S, Verma CS, Krishnaswamy P, Goh RSM, Chia I, Ho C, Low D, Virabhak S, Yong J, Zheng W, Seow SW, Seck YK, Koh M, Chambers JC, Tai ES, Tan P. Wong E, et al. Among authors: tirado magallanes r. Nat Genet. 2023 Feb;55(2):178-186. doi: 10.1038/s41588-022-01274-x. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658435 Review.
Analysis of clinically relevant variants from ancestrally diverse Asian genomes.
Chan SH, Bylstra Y, Teo JX, Kuan JL, Bertin N, Gonzalez-Porta M, Hebrard M, Tirado-Magallanes R, Tan JHJ, Jeyakani J, Li Z, Chai JF, Chong YS, Davila S, Goh LL, Lee ES, Wong E, Wong TY; SG10K_Health Consortium; Prabhakar S, Liu J, Cheng CY, Eisenhaber B, Karnani N, Leong KP, Sim X, Yeo KK, Chambers JC, Tai ES, Tan P, Jamuar SS, Ngeow J, Lim WK. Chan SH, et al. Among authors: tirado magallanes r. Nat Commun. 2022 Nov 5;13(1):6694. doi: 10.1038/s41467-022-34116-9. Nat Commun. 2022. PMID: 36335097 Free PMC article.
Whole genome DNA methylation: beyond genes silencing.
Tirado-Magallanes R, Rebbani K, Lim R, Pradhan S, Benoukraf T. Tirado-Magallanes R, et al. Oncotarget. 2017 Jan 17;8(3):5629-5637. doi: 10.18632/oncotarget.13562. Oncotarget. 2017. PMID: 27895318 Free PMC article. Review.
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity.
Yoon J, Grinchuk OV, Tirado-Magallanes R, Ngian ZK, Tay EXY, Chuah YH, Lee BWL, Feng J, Crasta KC, Ong CT, Benoukraf T, Ong DST. Yoon J, et al. Among authors: tirado magallanes r. Cell Death Differ. 2022 Jul;29(7):1379-1394. doi: 10.1038/s41418-021-00926-5. Epub 2022 Jan 20. Cell Death Differ. 2022. PMID: 35058574 Free PMC article.
TIP60 represses activation of endogenous retroviral elements.
Rajagopalan D, Tirado-Magallanes R, Bhatia SS, Teo WS, Sian S, Hora S, Lee KK, Zhang Y, Jadhav SP, Wu Y, Gan YH, Karnani N, Benoukraf T, Jha S. Rajagopalan D, et al. Among authors: tirado magallanes r. Nucleic Acids Res. 2018 Oct 12;46(18):9456-9470. doi: 10.1093/nar/gky659. Nucleic Acids Res. 2018. PMID: 30053221 Free PMC article.
Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance.
Numata A, Kwok HS, Zhou QL, Li J, Tirado-Magallanes R, Angarica VE, Hannah R, Park J, Wang CQ, Krishnan V, Rajagopalan D, Zhang Y, Zhou S, Welner RS, Osato M, Jha S, Bohlander SK, Göttgens B, Yang H, Benoukraf T, Lough JW, Bararia D, Tenen DG. Numata A, et al. Among authors: tirado magallanes r. Blood. 2020 Oct 8;136(15):1735-1747. doi: 10.1182/blood.2019001279. Blood. 2020. PMID: 32542325 Free PMC article.
A chemical biology approach reveals a dependency of glioblastoma on biotin distribution.
Yoon J, Grinchuk OV, Kannan S, Ang MJY, Li Z, Tay EXY, Lok KZ, Lee BWL, Chuah YH, Chia K, Tirado Magallanes R, Liu C, Zhao H, Hor JH, Lim JJ, Benoukraf T, Toh TB, Chow EK, Kovalik JP, Ching J, Ng SY, Koh MJ, Liu X, Verma CS, Ong DST. Yoon J, et al. Among authors: tirado magallanes r. Sci Adv. 2021 Sep 3;7(36):eabf6033. doi: 10.1126/sciadv.abf6033. Epub 2021 Sep 3. Sci Adv. 2021. PMID: 34516894 Free PMC article.
β-Catenin-TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation.
Danek P, Kardosova M, Janeckova L, Karkoulia E, Vanickova K, Fabisik M, Lozano-Asencio C, Benoukraf T, Tirado-Magallanes R, Zhou Q, Burocziova M, Rahmatova S, Pytlik R, Brdicka T, Tenen DG, Korinek V, Alberich-Jorda M. Danek P, et al. Among authors: tirado magallanes r. Blood. 2020 Nov 26;136(22):2574-2587. doi: 10.1182/blood.2019004664. Blood. 2020. PMID: 32822472 Free PMC article.
13 results