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Antibodies against alpha-synuclein: tools and therapies.
Vaikath NN, Hmila I, Gupta V, Erskine D, Ingelsson M, El-Agnaf OMA. Vaikath NN, et al. J Neurochem. 2019 Sep;150(5):612-625. doi: 10.1111/jnc.14713. Epub 2019 Jun 25. J Neurochem. 2019. PMID: 31055836 Free article. Review.
Uncovering a neurological protein signature for severe COVID-19.
El-Agnaf O, Bensmail I, Al-Nesf MAY, Flynn J, Taylor M, Majbour NK, Abdi IY, Vaikath NN, Farooq A, Vemulapalli PB, Schmidt F, Ouararhni K, Al-Siddiqi HH, Arredouani A, Wijten P, Al-Maadheed M, Mohamed-Ali V, Decock J, Abdesselem HB. El-Agnaf O, et al. Among authors: vaikath nn. Neurobiol Dis. 2023 Jun 15;182:106147. doi: 10.1016/j.nbd.2023.106147. Epub 2023 May 11. Neurobiol Dis. 2023. PMID: 37178811 Free PMC article.
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity.
Ghanem SS, Majbour NK, Vaikath NN, Ardah MT, Erskine D, Jensen NM, Fayyad M, Sudhakaran IP, Vasili E, Melachroinou K, Abdi IY, Poggiolini I, Santos P, Dorn A, Carloni P, Vekrellis K, Attems J, McKeith I, Outeiro TF, Jensen PH, El-Agnaf OMA. Ghanem SS, et al. Among authors: vaikath nn. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2109617119. doi: 10.1073/pnas.2109617119. Epub 2022 Mar 30. Proc Natl Acad Sci U S A. 2022. PMID: 35353605 Free PMC article.
Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system.
Schmidt F, Abdesselem HB, Suhre K, Vaikath NN, Sohail MU, Al-Nesf M, Bensmail I, Mashod F, Sarwath H, Bernhardt J, Schaefer-Ramadan S, Tan TM, Morris PE, Schenck EJ, Price D, Mohamed-Ali V, Al-Maadheed M, Arredouani A, Decock J, Blackburn JM, Choi AMK, El-Agnaf OM. Schmidt F, et al. Among authors: vaikath nn. Front Physiol. 2023 Jul 14;14:1203723. doi: 10.3389/fphys.2023.1203723. eCollection 2023. Front Physiol. 2023. PMID: 37520825 Free PMC article.
Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates.
Arotcarena ML, Dovero S, Prigent A, Bourdenx M, Camus S, Porras G, Thiolat ML, Tasselli M, Aubert P, Kruse N, Mollenhauer B, Trigo Damas I, Estrada C, Garcia-Carrillo N, Vaikath NN, El-Agnaf OMA, Herrero MT, Vila M, Obeso JA, Derkinderen P, Dehay B, Bezard E. Arotcarena ML, et al. Among authors: vaikath nn. Brain. 2020 May 1;143(5):1462-1475. doi: 10.1093/brain/awaa096. Brain. 2020. PMID: 32380543
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates.
Bourdenx M, Nioche A, Dovero S, Arotcarena ML, Camus S, Porras G, Thiolat ML, Rougier NP, Prigent A, Aubert P, Bohic S, Sandt C, Laferrière F, Doudnikoff E, Kruse N, Mollenhauer B, Novello S, Morari M, Leste-Lasserre T, Damas IT, Goillandeau M, Perier C, Estrada C, Garcia-Carrillo N, Recasens A, Vaikath NN, El-Agnaf OMA, Herrero MT, Derkinderen P, Vila M, Obeso JA, Dehay B, Bezard E. Bourdenx M, et al. Among authors: vaikath nn. Sci Adv. 2020 May 13;6(20):eaaz9165. doi: 10.1126/sciadv.aaz9165. eCollection 2020 May. Sci Adv. 2020. PMID: 32426502 Free PMC article.
Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort.
Smith M, Abdesselem HB, Mullins M, Tan TM, Nel AJM, Al-Nesf MAY, Bensmail I, Majbour NK, Vaikath NN, Naik A, Ouararhni K, Mohamed-Ali V, Al-Maadheed M, Schell DT, Baros-Steyl SS, Anuar ND, Ismail NH, Morris PE, Mamat RNR, Rosli NSM, Anwar A, Ellan K, Zain RM, Burgers WA, Mayne ES, El-Agnaf OMA, Blackburn JM. Smith M, et al. Among authors: vaikath nn. Viruses. 2021 Apr 28;13(5):786. doi: 10.3390/v13050786. Viruses. 2021. PMID: 33925055 Free PMC article.
34 results