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Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.
Sendler M, Weiss FU, Golchert J, Homuth G, van den Brandt C, Mahajan UM, Partecke LI, Döring P, Gukovsky I, Gukovskaya AS, Wagh PR, Lerch MM, Mayerle J. Sendler M, et al. Among authors: wagh pr. Gastroenterology. 2018 Feb;154(3):704-718.e10. doi: 10.1053/j.gastro.2017.10.018. Epub 2018 Jan 10. Gastroenterology. 2018. PMID: 29079517 Free PMC article.
Cancer Chemoprevention Using Nanotechnology-Based Approaches.
Desai P, Thumma NJ, Wagh PR, Zhan S, Ann D, Wang J, Prabhu S. Desai P, et al. Among authors: wagh pr. Front Pharmacol. 2020 Apr 3;11:323. doi: 10.3389/fphar.2020.00323. eCollection 2020. Front Pharmacol. 2020. PMID: 32317961 Free PMC article. Review.
Tumor-Specific Delivery of 5-Fluorouracil-Incorporated Epidermal Growth Factor Receptor-Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models.
Mahajan UM, Li Q, Alnatsha A, Maas J, Orth M, Maier SH, Peterhansl J, Regel I, Sendler M, Wagh PR, Mishra N, Xue Y, Allawadhi P, Beyer G, Kühn JP, Marshall T, Appel B, Lämmerhirt F, Belka C, Müller S, Weiss FU, Lauber K, Lerch MM, Mayerle J. Mahajan UM, et al. Among authors: wagh pr. Gastroenterology. 2021 Sep;161(3):996-1010.e1. doi: 10.1053/j.gastro.2021.05.055. Epub 2021 Jun 25. Gastroenterology. 2021. PMID: 34097885 Free article.
The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant.
Buchholz I, Nagel F, Klein A, Wagh PR, Mahajan UM, Greinacher A, Lerch MM, Mayerle J, Delcea M. Buchholz I, et al. Among authors: wagh pr. Biochim Biophys Acta Proteins Proteom. 2020 Jan;1868(1):140281. doi: 10.1016/j.bbapap.2019.140281. Epub 2019 Sep 13. Biochim Biophys Acta Proteins Proteom. 2020. PMID: 31525466 Free PMC article.