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Page 1
De novo design of potent and selective mimics of IL-2 and IL-15.
Silva DA, Yu S, Ulge UY, Spangler JB, Jude KM, Labão-Almeida C, Ali LR, Quijano-Rubio A, Ruterbusch M, Leung I, Biary T, Crowley SJ, Marcos E, Walkey CD, Weitzner BD, Pardo-Avila F, Castellanos J, Carter L, Stewart L, Riddell SR, Pepper M, Bernardes GJL, Dougan M, Garcia KC, Baker D. Silva DA, et al. Among authors: walkey cd. Nature. 2019 Jan;565(7738):186-191. doi: 10.1038/s41586-018-0830-7. Epub 2019 Jan 9. Nature. 2019. PMID: 30626941 Free PMC article.
The advent of de novo proteins for cancer immunotherapy.
Quijano-Rubio A, Ulge UY, Walkey CD, Silva DA. Quijano-Rubio A, et al. Among authors: walkey cd. Curr Opin Chem Biol. 2020 Jun;56:119-128. doi: 10.1016/j.cbpa.2020.02.002. Epub 2020 May 1. Curr Opin Chem Biol. 2020. PMID: 32371023 Free article. Review.
De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.
Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Barnes CO, Hsiang TY, Esser-Nobis K, Yu K, Reneer ZB, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric RS, Fuller DH, Walkey CD, Ross TM, Swanson R, Bjorkman PJ, Gale M Jr, Blancas-Mejia LM, Yen HL, Silva DA. Linsky TW, et al. Among authors: walkey cd. Science. 2020 Dec 4;370(6521):1208-1214. doi: 10.1126/science.abe0075. Epub 2020 Nov 5. Science. 2020. PMID: 33154107 Free PMC article.
De novo design of ACE2 protein decoys to neutralize SARS-CoV-2.
Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Hsiang TY, Esser-Nobis K, Yu K, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric R, Walkey CD, Swanson R, Gale M, Blancas-Mejia LM, Yen HL, Silva DA. Linsky TW, et al. Among authors: walkey cd. bioRxiv [Preprint]. 2020 Aug 3:2020.08.03.231340. doi: 10.1101/2020.08.03.231340. bioRxiv. 2020. PMID: 32793910 Free PMC article. Updated. Preprint.