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Page 1
GeneWeld: Efficient Targeted Integration Directed by Short Homology in Zebrafish.
Welker JM, Wierson WA, Almeida MP, Mann CM, Torrie ME, Ming Z, Ekker SC, Clark KJ, Dobbs DL, Essner JJ, McGrail M. Welker JM, et al. Among authors: wierson wa. Bio Protoc. 2021 Jul 20;11(14):e4100. doi: 10.21769/BioProtoc.4100. eCollection 2021 Jul 20. Bio Protoc. 2021. PMID: 34395736 Free PMC article.
Efficient targeted integration directed by short homology in zebrafish and mammalian cells.
Wierson WA, Welker JM, Almeida MP, Mann CM, Webster DA, Torrie ME, Weiss TJ, Kambakam S, Vollbrecht MK, Lan M, McKeighan KC, Levey J, Ming Z, Wehmeier A, Mikelson CS, Haltom JA, Kwan KM, Chien CB, Balciunas D, Ekker SC, Clark KJ, Webber BR, Moriarity BS, Solin SL, Carlson DF, Dobbs DL, McGrail M, Essner J. Wierson WA, et al. Elife. 2020 May 15;9:e53968. doi: 10.7554/eLife.53968. Elife. 2020. PMID: 32412410 Free PMC article.
Mesenchymal stromal cells with chimaeric antigen receptors for enhanced immunosuppression.
Sirpilla O, Sakemura RL, Hefazi M, Huynh TN, Can I, Girsch JH, Tapper EE, Cox MJ, Schick KJ, Manriquez-Roman C, Yun K, Stewart CM, Ogbodo EJ, Kimball BL, Mai LK, Gutierrez-Ruiz OL, Rodriguez ML, Gluscevic M, Larson DP, Abel AM, Wierson WA, Olivier G, Siegler EL, Kenderian SS. Sirpilla O, et al. Among authors: wierson wa. Nat Biomed Eng. 2024 Apr 1. doi: 10.1038/s41551-024-01195-6. Online ahead of print. Nat Biomed Eng. 2024. PMID: 38561490
The Gene Sculpt Suite: a set of tools for genome editing.
Mann CM, Martínez-Gálvez G, Welker JM, Wierson WA, Ata H, Almeida MP, Clark KJ, Essner JJ, McGrail M, Ekker SC, Dobbs D. Mann CM, et al. Among authors: wierson wa. Nucleic Acids Res. 2019 Jul 2;47(W1):W175-W182. doi: 10.1093/nar/gkz405. Nucleic Acids Res. 2019. PMID: 31127311 Free PMC article.
Expanding the CRISPR Toolbox with ErCas12a in Zebrafish and Human Cells.
Wierson WA, Simone BW, WareJoncas Z, Mann C, Welker JM, Kar B, Emch MJ, Friedberg I, Gendron WAC, Barry MA, Clark KJ, Dobbs DL, McGrail MA, Ekker SC, Essner JJ. Wierson WA, et al. CRISPR J. 2019 Dec;2(6):417-433. doi: 10.1089/crispr.2019.0026. Epub 2019 Nov 19. CRISPR J. 2019. PMID: 31742435 Free PMC article.
Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis.
Schultz-Rogers LE, Thayer ML, Kambakam S, Wierson WA, Helmer JA, Wishman MD, Wall KA, Greig JL, Forsman JL, Puchhalapalli K, Nair S, Weiss TJ, Luiken JM, Blackburn PR, Ekker SC, Kool M, McGrail M. Schultz-Rogers LE, et al. Among authors: wierson wa. Dev Dyn. 2022 Aug;251(8):1267-1290. doi: 10.1002/dvdy.467. Epub 2022 Mar 18. Dev Dyn. 2022. PMID: 35266256 Free PMC article.
GoldyTALEN Vectors with Improved Efficiency for Golden Gate TALEN Assembly.
Welker JM, Wierson WA, Wang Y, Poshusta TL, McNulty MS, Tisdale EE, Solin SL, Ekker SC, Clark KJ, McGrail M, Essner JJ. Welker JM, et al. Among authors: wierson wa. Hum Gene Ther. 2016 Jun;27(6):423-4. doi: 10.1089/hum.2016.012. Epub 2016 May 6. Hum Gene Ther. 2016. PMID: 27094430 Free PMC article. No abstract available.
Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation.
Schultz LE, Haltom JA, Almeida MP, Wierson WA, Solin SL, Weiss TJ, Helmer JA, Sandquist EJ, Shive HR, McGrail M. Schultz LE, et al. Among authors: wierson wa. Dis Model Mech. 2018 Jun 15;11(6):dmm034124. doi: 10.1242/dmm.034124. Dis Model Mech. 2018. PMID: 29914980 Free PMC article.