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PD-1 maintains CD8 T cell tolerance towards cutaneous neoantigens.
Damo M, Hornick NI, Venkat A, William I, Clulo K, Venkatesan S, He J, Fagerberg E, Loza JL, Kwok D, Tal A, Buck J, Cui C, Singh J, Damsky WE, Leventhal JS, Krishnaswamy S, Joshi NS. Damo M, et al. Among authors: william i. Nature. 2023 Jul;619(7968):151-159. doi: 10.1038/s41586-023-06217-y. Epub 2023 Jun 21. Nature. 2023. PMID: 37344588 Free PMC article.
Inducible de novo expression of neoantigens in tumor cells and mice.
Damo M, Fitzgerald B, Lu Y, Nader M, William I, Cheung JF, Connolly KA, Foster GG, Akama-Garren E, Lee DY, Chang GP, Gocheva V, Schmidt LM, Boileve A, Wilson JH, Cui C, Monroy I, Gokare P, Cabeceiras P, Jacks T, Joshi NS. Damo M, et al. Among authors: william i. Nat Biotechnol. 2021 Jan;39(1):64-73. doi: 10.1038/s41587-020-0613-1. Epub 2020 Jul 27. Nat Biotechnol. 2021. PMID: 32719479 Free PMC article.
A reservoir of stem-like CD8+ T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response.
Connolly KA, Kuchroo M, Venkat A, Khatun A, Wang J, William I, Hornick NI, Fitzgerald BL, Damo M, Kasmani MY, Cui C, Fagerberg E, Monroy I, Hutchins A, Cheung JF, Foster GG, Mariuzza DL, Nader M, Zhao H, Cui W, Krishnaswamy S, Joshi NS. Connolly KA, et al. Among authors: william i. Sci Immunol. 2021 Oct;6(64):eabg7836. doi: 10.1126/sciimmunol.abg7836. Epub 2021 Sep 2. Sci Immunol. 2021. PMID: 34597124 Free PMC article.
Methods for Detecting PER2:LUCIFERASE Bioluminescence Rhythms in Freely Moving Mice.
Martin-Burgos B, Wang W, William I, Tir S, Mohammad I, Javed R, Smith S, Cui Y, Arzavala J, Mora D, Smith CB, van der Vinne V, Molyneux PC, Miller SC, Weaver DR, Leise TL, Harrington ME. Martin-Burgos B, et al. Among authors: william i. J Biol Rhythms. 2022 Feb;37(1):78-93. doi: 10.1177/07487304211062829. Epub 2021 Dec 7. J Biol Rhythms. 2022. PMID: 34873943 Free PMC article.