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FBXO21 mediated degradation of p85α regulates proliferation and survival of acute myeloid leukemia.
Leukemia. 2023 Nov;37(11):2197-2208. doi: 10.1038/s41375-023-02020-w. Epub 2023 Sep 9.
Leukemia. 2023.
PMID: 37689825
Free PMC article.
Regulation of Normal and Malignant Hematopoiesis by FBOX Ubiquitin E3 Ligases.
Hynes-Smith RW, Wittorf KJ, Buckley SM.
Hynes-Smith RW, et al. Among authors: wittorf kj.
Trends Immunol. 2020 Dec;41(12):1128-1140. doi: 10.1016/j.it.2020.10.003. Epub 2020 Nov 4.
Trends Immunol. 2020.
PMID: 33160841
Free PMC article.
Review.
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Multi-omics reveals mitochondrial metabolism proteins susceptible for drug discovery in AML.
Caplan M, Wittorf KJ, Weber KK, Swenson SA, Gilbreath TJ, Willow Hynes-Smith R, Amador C, Hyde RK, Buckley SM.
Caplan M, et al. Among authors: wittorf kj.
Leukemia. 2022 May;36(5):1296-1305. doi: 10.1038/s41375-022-01518-z. Epub 2022 Feb 17.
Leukemia. 2022.
PMID: 35177813
Free PMC article.
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Ubiquitin E3 ligase FBXO21 regulates cytokine-mediated signaling pathways, but is dispensable for steady-state hematopoiesis.
Wittorf KJ, Weber KK, Swenson SA, Buckley SM.
Wittorf KJ, et al.
Exp Hematol. 2022 Oct;114:33-42.e3. doi: 10.1016/j.exphem.2022.08.002. Epub 2022 Aug 17.
Exp Hematol. 2022.
PMID: 35987460
Free article.
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Ubiquitin E3 Ligase FBXO9 Regulates Pluripotency by Targeting DPPA5 for Ubiquitylation and Degradation.
Swenson SA, Dobish KK, Peters HC, Bea Winship C, Willow Hynes-Smith R, Caplan M, Wittorf KJ, Ghosal G, Buckley SM.
Swenson SA, et al. Among authors: wittorf kj.
Stem Cells. 2024 Apr 15;42(4):317-328. doi: 10.1093/stmcls/sxae004.
Stem Cells. 2024.
PMID: 38227647
Free PMC article.
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Loss of FBXO9 Enhances Proteasome Activity and Promotes Aggressiveness in Acute Myeloid Leukemia.
Hynes-Smith RW, Swenson SA, Vahle H, Wittorf KJ, Caplan M, Amador C, Hyde RK, Buckley SM.
Hynes-Smith RW, et al. Among authors: wittorf kj.
Cancers (Basel). 2019 Nov 3;11(11):1717. doi: 10.3390/cancers11111717.
Cancers (Basel). 2019.
PMID: 31684170
Free PMC article.
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