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Neurodevelopmental disorders, like cancer, are connected to impaired chromatin remodelers, PI3K/mTOR, and PAK1-regulated MAPK.
Biophys Rev. 2023 Apr 1;15(2):163-181. doi: 10.1007/s12551-023-01054-9. eCollection 2023 Apr.
Biophys Rev. 2023.
PMID: 37124926
Free PMC article.
Review.
Mechanism of activation and the rewired network: New drug design concepts.
Nussinov R, Zhang M, Maloney R, Tsai CJ, Yavuz BR, Tuncbag N, Jang H.
Nussinov R, et al. Among authors: yavuz br.
Med Res Rev. 2022 Mar;42(2):770-799. doi: 10.1002/med.21863. Epub 2021 Oct 25.
Med Res Rev. 2022.
PMID: 34693559
Free PMC article.
Review.
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Pan-cancer clinical impact of latent drivers from double mutations.
Yavuz BR, Tsai CJ, Nussinov R, Tuncbag N.
Yavuz BR, et al.
Commun Biol. 2023 Feb 20;6(1):202. doi: 10.1038/s42003-023-04519-5.
Commun Biol. 2023.
PMID: 36808143
Free PMC article.
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Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome.
Yavuz BR, Arici MK, Demirel HC, Tsai CJ, Jang H, Nussinov R, Tuncbag N.
Yavuz BR, et al.
NPJ Genom Med. 2023 Nov 4;8(1):37. doi: 10.1038/s41525-023-00377-6.
NPJ Genom Med. 2023.
PMID: 37925498
Free PMC article.
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