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Page 1
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Jackow J, Rami A, Hansen C, Guo Z, Gaddam S, Pappalardo A, Li L, Cramer A, Roy KR, Nguyen TM, Tanabe K, McGrath PS, Bruckner A, Bilousova G, Roop D, Bailey I, Tang JY, Christiano A, Steinmetz LM, Wernig M, Oro AE. Neumayer G, et al. Among authors: zhen hh. bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.529447. doi: 10.1101/2023.02.28.529447. bioRxiv. 2023. PMID: 36909618 Free PMC article. Preprint.
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.
Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, Li R, Wernig M, Wong WH, Chang HY, Oro AE. Li L, et al. Among authors: zhen hh. Cell Stem Cell. 2019 Feb 7;24(2):271-284.e8. doi: 10.1016/j.stem.2018.12.012. Epub 2019 Jan 24. Cell Stem Cell. 2019. PMID: 30686763 Free PMC article.
Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment.
Pattison JM, Melo SP, Piekos SN, Torkelson JL, Bashkirova E, Mumbach MR, Rajasingh C, Zhen HH, Li L, Liaw E, Alber D, Rubin AJ, Shankar G, Bao X, Chang HY, Khavari PA, Oro AE. Pattison JM, et al. Among authors: zhen hh. Nat Genet. 2018 Dec;50(12):1658-1665. doi: 10.1038/s41588-018-0263-0. Epub 2018 Nov 5. Nat Genet. 2018. PMID: 30397335 Free PMC article.
Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa.
Sebastiano V, Zhen HH, Haddad B, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, Schwertschkow A, Bauer G, Lisowski L, Kay MA, Kim SK, Lane AT, Wernig M, Oro AE. Sebastiano V, et al. Among authors: zhen hh. Sci Transl Med. 2014 Nov 26;6(264):264ra163. doi: 10.1126/scitranslmed.3009540. Sci Transl Med. 2014. PMID: 25429056 Free PMC article.
Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation.
Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Sneddon JB, et al. Among authors: zhen hh. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14842-7. doi: 10.1073/pnas.0606857103. Epub 2006 Sep 26. Proc Natl Acad Sci U S A. 2006. PMID: 17003113 Free PMC article.
11 results