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Allosteric interactions prime androgen receptor dimerization and activation.
Wasmuth EV, Broeck AV, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W, Watson PA, Zinder JC, Karthaus WR, de la Cruz MJ, Hite RK, Manova-Todorova K, Yu Z, Weintraub ST, Klinge S, Sawyers CL. Wasmuth EV, et al. Among authors: zinder jc. Mol Cell. 2022 Jun 2;82(11):2021-2031.e5. doi: 10.1016/j.molcel.2022.03.035. Epub 2022 Apr 20. Mol Cell. 2022. PMID: 35447082 Free PMC article.
Shelterin is a dimeric complex with extensive structural heterogeneity.
Zinder JC, Olinares PDB, Svetlov V, Bush MW, Nudler E, Chait BT, Walz T, de Lange T. Zinder JC, et al. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2201662119. doi: 10.1073/pnas.2201662119. Epub 2022 Jul 26. Proc Natl Acad Sci U S A. 2022. PMID: 35881804 Free PMC article.
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