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Page 1
Acetylation discriminates disease-specific tau deposition.
Chakraborty P, Rivière G, Hebestreit A, de Opakua AI, Vorberg IM, Andreas LB, Zweckstetter M. Chakraborty P, et al. Among authors: de opakua ai. Nat Commun. 2023 Sep 22;14(1):5919. doi: 10.1038/s41467-023-41672-1. Nat Commun. 2023. PMID: 37739953 Free PMC article.
The Gαi-GIV binding interface is a druggable protein-protein interaction.
DiGiacomo V, de Opakua AI, Papakonstantinou MP, Nguyen LT, Merino N, Blanco-Canosa JB, Blanco FJ, Garcia-Marcos M. DiGiacomo V, et al. Among authors: de opakua ai. Sci Rep. 2017 Aug 17;7(1):8575. doi: 10.1038/s41598-017-08829-7. Sci Rep. 2017. PMID: 28819150 Free PMC article.
Double Monoubiquitination Modifies the Molecular Recognition Properties of p15PAF Promoting Binding to the Reader Module of Dnmt1.
González-Magaña A, de Opakua AI, Merino N, Monteiro H, Diercks T, Murciano-Calles J, Luque I, Bernadó P, Cordeiro TN, Biasio A, Blanco FJ. González-Magaña A, et al. Among authors: de opakua ai. ACS Chem Biol. 2019 Oct 18;14(10):2315-2326. doi: 10.1021/acschembio.9b00679. Epub 2019 Sep 18. ACS Chem Biol. 2019. PMID: 31479228 Free article.
Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.
Corral-Rodríguez MÁ, Stuiver M, Abascal-Palacios G, Diercks T, Oyenarte I, Ereño-Orbea J, de Opakua AI, Blanco FJ, Encinar JA, Spiwok V, Terashima H, Accardi A, Müller D, Martínez-Cruz LA. Corral-Rodríguez MÁ, et al. Among authors: de opakua ai. Biochem J. 2014 Nov 15;464(1):23-34. doi: 10.1042/BJ20140409. Biochem J. 2014. PMID: 25184538 Free PMC article.