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Page 1
Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection.
Brouwer PJM, Antanasijevic A, Ronk AJ, Müller-Kräuter H, Watanabe Y, Claireaux M, Perrett HR, Bijl TPL, Grobben M, Umotoy JC, Schriek AI, Burger JA, Tejjani K, Lloyd NM, Steijaert TH, van Haaren MM, Sliepen K, de Taeye SW, van Gils MJ, Crispin M, Strecker T, Bukreyev A, Ward AB, Sanders RW. Brouwer PJM, et al. Among authors: van haaren mm. Cell Host Microbe. 2022 Dec 14;30(12):1759-1772.e12. doi: 10.1016/j.chom.2022.10.018. Epub 2022 Nov 17. Cell Host Microbe. 2022. PMID: 36400021 Free PMC article.
Natural infection as a blueprint for rational HIV vaccine design.
van Haaren MM, van den Kerkhof TL, van Gils MJ. van Haaren MM, et al. Hum Vaccin Immunother. 2017 Jan 2;13(1):229-236. doi: 10.1080/21645515.2016.1232785. Epub 2016 Sep 20. Hum Vaccin Immunother. 2017. PMID: 27649455 Free PMC article. Review.
Anti-HIV-1 Nanobody-IgG1 Constructs With Improved Neutralization Potency and the Ability to Mediate Fc Effector Functions.
Schriek AI, van Haaren MM, Poniman M, Dekkers G, Bentlage AEH, Grobben M, Vidarsson G, Sanders RW, Verrips T, Geijtenbeek TBH, Heukers R, Kootstra NA, de Taeye SW, van Gils MJ. Schriek AI, et al. Among authors: van haaren mm. Front Immunol. 2022 May 16;13:893648. doi: 10.3389/fimmu.2022.893648. eCollection 2022. Front Immunol. 2022. PMID: 35651621 Free PMC article.
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability.
Brouwer PJM, Caniels TG, van der Straten K, Snitselaar JL, Aldon Y, Bangaru S, Torres JL, Okba NMA, Claireaux M, Kerster G, Bentlage AEH, van Haaren MM, Guerra D, Burger JA, Schermer EE, Verheul KD, van der Velde N, van der Kooi A, van Schooten J, van Breemen MJ, Bijl TPL, Sliepen K, Aartse A, Derking R, Bontjer I, Kootstra NA, Wiersinga WJ, Vidarsson G, Haagmans BL, Ward AB, de Bree GJ, Sanders RW, van Gils MJ. Brouwer PJM, et al. Among authors: van haaren mm. Science. 2020 Aug 7;369(6504):643-650. doi: 10.1126/science.abc5902. Epub 2020 Jun 15. Science. 2020. PMID: 32540902 Free PMC article.
Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates.
Reiss EIMM, van Haaren MM, van Schooten J, Claireaux MAF, Maisonnasse P, Antanasijevic A, Allen JD, Bontjer I, Torres JL, Lee WH, Ozorowski G, Vázquez Bernat N, Kaduk M, Aldon Y, Burger JA, Chawla H, Aartse A, Tolazzi M, Gao H, Mundsperger P, Crispin M, Montefiori DC, Karlsson Hedestam GB, Scarlatti G, Ward AB, Le Grand R, Shattock R, Dereuddre-Bosquet N, Sanders RW, van Gils MJ. Reiss EIMM, et al. Among authors: van haaren mm. NPJ Vaccines. 2022 Nov 25;7(1):152. doi: 10.1038/s41541-022-00576-9. NPJ Vaccines. 2022. PMID: 36433972 Free PMC article.
Corrigendum: Anti-HIV-1 nanobody-IgG1 constructs with improved neutralization potency and the ability to mediate Fc effector functions.
Schriek AI, van Haaren MM, Poniman M, Dekkers G, Bentlage AEH, Grobben M, Vidarsson G, Sanders RW, Verrips T, Geijtenbeek TBH, Heukers R, Kootstra NA, de Taeye SW, van Gils MJ. Schriek AI, et al. Among authors: van haaren mm. Front Immunol. 2022 Nov 22;13:1091668. doi: 10.3389/fimmu.2022.1091668. eCollection 2022. Front Immunol. 2022. PMID: 36483568 Free PMC article.
Primary antibody response after influenza virus infection is first dominated by low-mutated HA-stem antibodies followed by higher-mutated HA-head antibodies.
Aartse A, Mortier D, Mooij P, Hofman S, van Haaren MM, Corcoran M, Karlsson Hedestam GB, Eggink D, Claireaux M, Bogers WMJM, van Gils MJ, Koopman G. Aartse A, et al. Among authors: van haaren mm. Front Immunol. 2022 Nov 3;13:1026951. doi: 10.3389/fimmu.2022.1026951. eCollection 2022. Front Immunol. 2022. PMID: 36405682 Free PMC article.
Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.
van Schooten J, van Haaren MM, Li H, McCoy LE, Havenar-Daughton C, Cottrell CA, Burger JA, van der Woude P, Helgers LC, Tomris I, Labranche CC, Montefiori DC, Ward AB, Burton DR, Moore JP, Sanders RW, Crotty S, Shaw GM, van Gils MJ. van Schooten J, et al. Among authors: van haaren mm. PLoS Pathog. 2021 Aug 25;17(8):e1009736. doi: 10.1371/journal.ppat.1009736. eCollection 2021 Aug. PLoS Pathog. 2021. PMID: 34432859 Free PMC article.
Antibodies from Rabbits Immunized with HIV-1 Clade B SOSIP Trimers Can Neutralize Multiple Clade B Viruses by Destabilizing the Envelope Glycoprotein.
van Haaren MM, McCoy LE, Torres JL, Lee W, Cottrell CA, Copps JL, van der Woude P, Yasmeen A, de Taeye SW, Torrents de la Peña A, Moore JP, Burton DR, Klasse PJ, Ward AB, Sanders RW, van Gils MJ. van Haaren MM, et al. J Virol. 2021 Aug 10;95(17):e0009421. doi: 10.1128/JVI.00094-21. Epub 2021 Aug 10. J Virol. 2021. PMID: 34076487 Free PMC article.