User profiles for Ø Ødegård-Fougner

Øyvind Ødegård Fougner

Oslo University Hospital
Verified email at ous-research.no
Cited by 190

A quantitative map of human Condensins provides new insights into mitotic chromosome architecture

…, B Koch, M Kueblbeck, Ø Ødegård-Fougner… - Journal of Cell …, 2018 - rupress.org
Ødegård-Fougner were supported by the European Molecular Biology Laboratory … Ø.
Ødegård-Fougner and N. Walther set up the pipeline for automated spot detection and clustering, …

Visualization of loop extrusion by DNA nanoscale tracing in single human cells

KS Beckwith, Ø Ødegård-Fougner, NR Morero… - BioRxiv, 2021 - biorxiv.org
The spatial organization of the genome is essential for its functions, including gene
expression, DNA replication and repair, as well as chromosome segregation 1 . Biomolecular …

[HTML][HTML] Nanoscale 3D DNA tracing in single human cells visualizes loop extrusion directly in situ

K Beckwith, Ø Ødegård-Fougner, N Morero, C Barton… - 2021 - europepmc.org
The spatial organization of the genome is essential for its functions, including gene
expression, DNA replication and repair, as well as chromosome segregation. Biomolecular …

[HTML][HTML] ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy

…, S Morganella, Ø Ødegård-Fougner… - PLoS computational …, 2018 - journals.plos.org
The 3D structure of chromatin plays a key role in genome function, including gene expression,
DNA replication, chromosome segregation, and DNA repair. Furthermore the location of …

The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection

…, Ø ØdegårdFougner, Ø Strømland… - The FEBS …, 2020 - Wiley Online Library
Chromatin post‐translational modifications are thought to be important for epigenetic effects
on gene expression. Methylation of histone N‐terminal tail lysine residues constitutes one of …

[HTML][HTML] Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix

…, O Dobrovolska, Ø Ødegård-Fougner… - Frontiers in Molecular …, 2022 - frontiersin.org
The CW domain binds to histone tail modifications found in different protein families involved
in epigenetic regulation and chromatin remodeling. CW domains recognize the methylation …

1H, 13C, and 15N resonance assignments of CW domain of the N-methyltransferase ASHH2 free and bound to the mono-, di- and tri-methylated histone H3 tail …

…, Ø Ødegård-Fougner, R Aasland, Ø Halskau - Biomolecular NMR …, 2018 - Springer
The ASHH2 CW domain is responsible for recognizing the methylation state at lysine 4 of
histone 3 N-terminal tails and implicated in the recruitment of the ASHH2 methyltransferase …

[CITATION][C] A Method to Image the 3D Structure of Human Genes in Single Cells with 10 Kb Resolution

ØØ Fougner - 2019 - Ruperto Carola University …

Bridging condensins mediate compaction of mitotic chromosomes

G Forte, L Boteva, F Conforto, N Gilbert, PR Cook… - Journal of Cell …, 2024 - rupress.org
Eukaryotic chromosomes compact during mitosis into elongated cylinders—and not the
spherical globules expected of selfattracting long flexible polymers. This process is mainly driven …

Dual spindles assemble in bovine zygotes despite the presence of paternal centrosomes

I Schneider, M de Ruijter-Villani, MJ Hossain… - Journal of Cell …, 2021 - rupress.org
The first mitosis of the mammalian embryo must partition the parental genomes contained in
two pronuclei. In rodent zygotes, sperm centrosomes are degraded, and instead, acentriolar …