Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the
canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA …

A number of reports suggest that the sexually transmitted pathogen of cattle, Tritrichomonas
foetus, and a gastrointestinal commensal of pigs, Tritrichomonas suis, are very similar and …

N6-methyladenosine (m 6 A) and N6,2′-O-dimethyladenosine (m 6 Am) are two abundant
modifications found in mRNAs and ncRNAs that can regulate multiple aspects of RNA …

Most eukaryotic RNAs are posttranscriptionally modified. The majority of modifications
promote RNA maturation, others may regulate function and stability. The 3′ terminal non-…

Eukaryotes have evolved elaborate splicing mechanisms to remove introns that would
otherwise destroy the protein-coding capacity of genes. Nuclear premRNA splicing requires …

Background Despite the medical importance of trichomoniasis, little is known about the
genetic relatedness of Trichomonas vaginalis strains with similar biological characteristics. …

We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted
human pathogen. Repeats and transposable elements comprise about two-thirds of the …

The main function of the hydrogenosome, a typical organelle of trichomonads, is to convert
malate or pyruvate to H 2 , CO 2 and acetate by a pathway associated with ATP synthesis. …

N6-methyladenosine (m 6 A) is the most abundant base modification found in messenger
RNAs (mRNAs). The discovery of FTO as the first m 6 A mRNA demethylase established the …

Eukaryotic mRNAs are modified by several chemical marks which have significant impacts
on mRNA biology, gene expression, and cellular metabolism as well as on the survival and …