Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
…, A Amlie-Wolf, C Bellenguez, A Frizatti… - Nature …, 2019 - nature.com
Risk for late-onset Alzheimer’s disease (LOAD), the most prevalent dementia, is partially
driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association …
driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association …
Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing
…, SJ van der Lee, A Amlie-Wolf, C Bellenguez, A Frizatti… - BioRxiv, 2018 - biorxiv.org
Introduction Late-onset Alzheimer’s disease (LOAD, onset age > 60 years) is the most
prevalent dementia in the elderly 1 , and risk is partially driven by genetics 2 . Many of the loci …
prevalent dementia in the elderly 1 , and risk is partially driven by genetics 2 . Many of the loci …
[PDF][PDF] Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing …
…, A Amlie-Wolf, C Bellenguez, A Frizatti… - Nature …, 2019 - ricerca.uniba.it
… van der Lee , Alexandre Amlie-Wolf , Céline Bellenguez , Aura Frizatti, Vincent Chouraki,
Eden R. Martin, Kristel Sleegers , Nandini Badarinarayan, Johanna Jakobsdottir, Kara L. …
Eden R. Martin, Kristel Sleegers , Nandini Badarinarayan, Johanna Jakobsdottir, Kara L. …
[CITATION][C] Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A beta, tau, immunity and lipid processing (vol 51, pg 414 …
…, A Amlie-Wolf, C Bellenguez, A Frizatti… - Nature …, 2019 - Nature Research
Brain cell type–specific enhancer–promoter interactome maps and disease-risk association
Noncoding genetic variation is a major driver of phenotypic diversity, but functional interpretation
is challenging. To better understand common genetic variation associated with brain …
is challenging. To better understand common genetic variation associated with brain …
Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases
Dementia is a rapidly rising global health crisis that silently disables families and ends lives
and livelihoods around the world. To date, however, no early biomarkers or effective …
and livelihoods around the world. To date, however, no early biomarkers or effective …
Gut microbiome composition may be an indicator of preclinical Alzheimer's disease
Alzheimer’s disease (AD) pathology is thought to progress from normal cognition through
preclinical disease and ultimately to symptomatic AD with cognitive impairment. Recent work …
preclinical disease and ultimately to symptomatic AD with cognitive impairment. Recent work …
[CITATION][C] Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer's Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic …
…, SJ van der Lee, A Amlie-Wolf, C Bellenguez, A Frizatti… - Nat Genet, 2019
[CITATION][C] Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer's Disease Consortium (GERAD/PERADES) …
…, A Amlie-Wolf, C Bellenguez, A Frizatti… - Nat Genet, 2019
[CITATION][C] European Alzheimer's Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and …
…, SJ van der Lee, A Amlie-Wolf, C Bellenguez, A Frizatti… - Nat Genet, 2019