[HTML][HTML] Immunosenescence and inflamm-aging as two sides of the same coin: friends or foes?
The immune system is the most important protective physiological system of the organism. It
has many connections with other systems and is, in fact, often considered as part of the …
has many connections with other systems and is, in fact, often considered as part of the …
[HTML][HTML] The physical frailty syndrome as a transition from homeostatic symphony to cacophony
Frailty in aging marks a state of decreased reserves resulting in increased vulnerability to
adverse outcomes when exposed to stressors. This Perspective synthesizes the evidence on …
adverse outcomes when exposed to stressors. This Perspective synthesizes the evidence on …
[HTML][HTML] Immunology of aging: the birth of inflammaging
The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response to a …
evolutionary or rather a revolutionary conceptualization of the immune changes in response to a …
[BOOK][B] News around the world: Content, practitioners, and the public
PJ Shoemaker, AA Cohen - 2012 - books.google.com
… more confident that she needed Cohen to help her do the … who knew about such studies,
Cohen said. Since Shoemaker and … on the study protocols and visited Cohen in Tel Aviv later in …
Cohen said. Since Shoemaker and … on the study protocols and visited Cohen in Tel Aviv later in …
Dynamic proteomics of individual cancer cells in response to a drug
Why do seemingly identical cells respond differently to a drug? To address this, we studied
the dynamics and variability of the protein response of human cancer cells to a …
the dynamics and variability of the protein response of human cancer cells to a …
Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice
AA Cohen, PNP Gnanapragasam, YE Lee, PR Hoffman… - Science, 2021 - science.org
Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and
SARS-related emergent zoonotic coronaviruses is urgently needed. We made homotypic …
SARS-related emergent zoonotic coronaviruses is urgently needed. We made homotypic …
Immune checkpoint inhibitor rechallenge after immune-related adverse events in patients with cancer
…, M Sassier, J Cautela, F Thuny, AA Cohen… - JAMA …, 2020 - jamanetwork.com
Importance Limited information is available on the safety of a rechallenge with an immune
checkpoint inhibitor (ICI) after an immune-related adverse event (irAE). Objective To identify …
checkpoint inhibitor (ICI) after an immune-related adverse event (irAE). Objective To identify …
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
To combat future severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health, …
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health, …
Initiation of sacubitril/valsartan in haemodynamically stabilised heart failure patients in hospital or early after discharge: primary results of the randomised …
…, M Kaislerova, Z Motovska, AA Cohen… - European journal of …, 2019 - Wiley Online Library
Aims To assess tolerability and optimal time point for initiation of sacubitril/valsartan in
patients stabilised after acute heart failure (AHF). Methods and results TRANSITION was a …
patients stabilised after acute heart failure (AHF). Methods and results TRANSITION was a …
Adult and child malaria mortality in India: a nationally representative mortality survey
Background National malaria death rates are difficult to assess because reliably diagnosed
malaria is likely to be cured, and deaths in the community from undiagnosed malaria could …
malaria is likely to be cured, and deaths in the community from undiagnosed malaria could …