The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain
uncharacterized, and their roles in shaping the gut microbiome and in impacting on human …

Studies of inflammatory bowel disease (IBD) have been inconclusive in relating microbiota
with distribution of inflammation. We report microbiota, host transcriptomics, epigenomics and …

Rapid advancements in sequencing technologies along with falling costs present widespread
opportunities for microbiome studies across a vast and diverse array of environments. …

… In this study, Clooney et al. describe changes in the composition and function of the human
gut virome by analyzing both known and unknown viral sequences. They provide evidence …

Background Next-generation sequencing platforms have revolutionised our ability to
investigate the microbiota composition of complex environments, frequently through 16S rRNA …

Objective The microbiome contributes to the pathogenesis of inflammatory bowel disease (IBD)
but the relative contribution of different lifestyle and environmental factors to the …

CrAssphages represent the most abundant virus in the human gut microbiota, but the lack of
available genome sequences for comparison has kept them enigmatic. Recently, sequence-…

Background Proton pump inhibitor ( PPI ) use is associated with an increased risk of Clostridium
difficile infection ( CDI ), though the mechanism is unclear. PPI induced alterations to the …

… Clooney contributed equally to this work. The error has been corrected for the HTML, PDF
and … Clooney, AG et al. Comparing apples and oranges?: Next generation sequencing and its …

Background The viral component of microbial communities plays a vital role in driving bacterial
diversity, facilitating nutrient turnover and shaping community composition. Despite their …