Patients with mental disorders show many biological abnormalities which distinguish them
from normal volunteers; however, few of these have led to tests with clinical utility. Several …

Huntington's disease (HD) is an incurable neuropsychiatric disease associated with CAG
repeat expansion within a widely expressed gene that causes selective neuronal death. To …

We have produced yeast artificial chromosome (YAC) transgenic mice expressing normal (YAC18)
and mutant (YAC46 and YAC72) huntingtin (htt) in a developmental and tissue-…

The hippocampus, the prefrontal cortex, and the ventral striatum form interconnected neural
circuits that may underlie aspects of spatial cognition and memory. In the present series of …

Functional traits offer a rich quantitative framework for developing and testing theories in
evolutionary biology, ecology and ecosystem science. However, the potential of functional traits …

Dopamine (DA) within the prefrontal cortex (PFC) plays an important role in modulating the
short-term retention of information during working memory tasks. In contrast, little is known …

Central dopamine transmission was examined in the nucleus accumbens and striatum of
sexually experienced male rats during mating behaviour using in vivo brain microdialysis. …

… of the effluent from the accumbens probe was carried out on a BAS amperometric detector
Model LC4B that contained a glassy carbon working electrode set to 700 mV against the Ag–…

1.3. The sensorimotor syndrome 2. Dopamine and feeding behaviours 2.1. Dopamine
antagonists and consummatory behaviours 2.1. 1. Initiation of consummatory behaviours 2.1. 2. …

The effects of reversible lidocaine-induced lesions of 2 subregions of the rat medial prefrontal
cortex (mPFC) were examined on a series of cognitively based foraging behaviors on a …