Candidate phyla radiation (CPR) bacteria and DPANN (an acronym of the names of the first
included phyla) archaea are massive radiations of organisms that are widely distributed …

The assembly of single-amplified genomes (SAGs) and metagenome-assembled genomes (MAGs)
has led to a surge in genome-based discoveries of members affiliated with Archaea …

The tree of life is one of the most important organizing principles in biology 1. Gene surveys
suggest the existence of an enormous number of branches 2, but even an approximation of …

The subterranean world hosts up to one-fifth of all biomass, including microbial communities
that drive transformations central to Earth’s biogeochemical cycles. However, little is known …

… higher for the 0.2 μm sample (DAS Tool: 36 genomes, Probst: 32) and even higher for the
3.0 μm sample (DAS Tool: 38, Probst: 31). For both samples a larger number of draft genomes …

CRISPR–Cas systems provide microbes with adaptive immunity by employing short DNA
sequences, termed spacers, that guide Cas proteins to cleave foreign DNA 1 , 2 . Class 2 …

Bacteriophages typically have small genomes 1 and depend on their bacterial hosts for
replication 2 . Here we sequenced DNA from diverse ecosystems and found hundreds of phage …

High-throughput RNA sequencing offers broad opportunities to explore the Earth RNA
virome. Mining 5,150 diverse metatranscriptomes uncovered >2.5 million RNA virus contigs. …

Most prokaryotes are not available as pure cultures and therefore ineligible for naming under
the rules and recommendations of the International Code of Nomenclature of Prokaryotes (…

An enormous diversity of previously unknown bacteria and archaea has been discovered
recently, yet their functional capacities and distributions in the terrestrial subsurface remain …