[HTML][HTML] Two tongues, one brain: imaging bilingual speech production
This review considers speaking in a second language from the perspective of motor–sensory
control. Previous studies relating brain function to the prior acquisition of two or more …
control. Previous studies relating brain function to the prior acquisition of two or more …
[PDF][PDF] Peroxisome-mediated metabolism is required for immune response to microbial infection
The innate immune response is critical for animal homeostasis and is conserved from
invertebrates to vertebrates. This response depends on specialized cells that recognize, internalize…
invertebrates to vertebrates. This response depends on specialized cells that recognize, internalize…
Molecular interactions between Vestigial and Scalloped promote wing formation in Drosophila
AJ Simmonds, X Liu, KH Soanes… - Genes & …, 1998 - genesdev.cshlp.org
Scalloped (Sd) and Vestigial (Vg) are each needed forDrosophila wing development. We
show that Sd is required for Vg function and that altering their relative cellular levels inhibits …
show that Sd is required for Vg function and that altering their relative cellular levels inhibits …
The chemotherapeutic agent paclitaxel inhibits autophagy through two distinct mechanisms that regulate apoptosis
…, DR Hemmerling, R Odsen, T Simmen, AJ Simmonds… - Oncogene, 2013 - nature.com
Anti-mitotic agents such as paclitaxel and docetaxel are widely used for the treatment of
breast, ovarian and lung cancers. Although paclitaxel induces apoptosis, this drug also …
breast, ovarian and lung cancers. Although paclitaxel induces apoptosis, this drug also …
Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency
…, A Ansari, J Sanderson, RA De Abreu, AH Simmonds… - Human genetics, 2002 - Springer
Inosine triphosphate pyrophosphohydrolase (ITPase) deficiency is a common inherited
condition characterized by the abnormal accumulation of inosine triphosphate (ITP) in …
condition characterized by the abnormal accumulation of inosine triphosphate (ITP) in …
[HTML][HTML] Apical localization of wingless transcripts is required for wingless signaling
AJ Simmonds, I Livne-Bar, HM Krause - Cell, 2001 - cell.com
Many developing and adult tissues are comprised of polarized epithelia. Proteins that are
asymmetrically distributed in these cells are thought to be localized by protein trafficking. Here …
asymmetrically distributed in these cells are thought to be localized by protein trafficking. Here …
The use of elemental sulfur as an alternative feedstock for polymeric materials
…, JJ Griebel, ET Kim, H Yoon, AG Simmonds… - Nature …, 2013 - nature.com
An excess of elemental sulfur is generated annually from hydrodesulfurization in petroleum
refining processes; however, it has a limited number of uses, of which one example is the …
refining processes; however, it has a limited number of uses, of which one example is the …
[HTML][HTML] Drosophila mRNA localization during later development: past, present, and future
SC Hughes, AJ Simmonds - Frontiers in genetics, 2019 - frontiersin.org
Multiple mechanisms tightly regulate mRNAs during their transcription, translation, and
degradation. Of these, the physical localization of mRNAs to specific cytoplasmic regions is …
degradation. Of these, the physical localization of mRNAs to specific cytoplasmic regions is …
Distinguishable functions for engrailed and Invected in anterior–posterior patterning in the Drosopila wing
AJ Simmonds, WJ Brook, SM Cohen, JB Bell - Nature, 1995 - nature.com
SUBDIVISION of the limb primordia into compartments initiates pattern formation in the
developing limbs 1,2 . Interaction between distinctly specific cells in adjacent compartments leads …
developing limbs 1,2 . Interaction between distinctly specific cells in adjacent compartments leads …
[HTML][HTML] Rosy Beginnings: Studying Peroxisomes in Drosophila
C Pridie, K Ueda, AJ Simmonds - Frontiers in Cell and …, 2020 - frontiersin.org
Research using the fruit fly Drosophila melanogaster has traditionally focused on understanding
how mutations affecting gene regulation or function affect processes linked to animal …
how mutations affecting gene regulation or function affect processes linked to animal …