User profiles for A. K. Henders

Anjali Henders

Institute for Molecular Biosciences, The University of Queensland
Verified email at uq.edu.au
Cited by 29087

Common SNPs explain a large proportion of the heritability for human height

…, B Benyamin, BP McEvoy, S Gordon, AK Henders… - Nature …, 2010 - nature.com
SNPs discovered by genome-wide association studies (GWASs) account for only a small
fraction of the genetic variation of complex traits in human populations. Where is the remaining …

Defining the role of common variation in the genomic and biological architecture of adult human height

…, NL Heard-Costa, Q Helmer, G Hemani, AK Henders… - Nature …, 2014 - nature.com
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …

[HTML][HTML] DNA methylation age of blood predicts all-cause mortality in later life

…, E Colicino, SE Harris, J Gibson, AK Henders… - Genome biology, 2015 - Springer
Background DNA methylation levels change with age. Recent studies have identified
biomarkers of chronological age based on DNA methylation levels. It is not yet known whether …

Identification of seven loci affecting mean telomere length and their association with disease

…, K Garlaschelli, D Guo, AL Hartikainen, AK Henders… - Nature …, 2013 - nature.com
Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer
and several age-associated diseases. We report here a genome-wide meta-analysis of …

[HTML][HTML] The transcriptional landscape of age in human peripheral blood

…, V Salomaa, AK Henders, NG Martin, AK Smith… - Nature …, 2015 - nature.com
Disease incidences increase with age, but the molecular characteristics of ageing that lead
to increased disease susceptibility remain inadequately understood. Here we perform a …

The anorexia nervosa genetics initiative (ANGI): overview and methods

…, JH Baker, A Juréus, R Parker, AK Henders… - Contemporary Clinical …, 2018 - Elsevier
Background Genetic factors contribute to anorexia nervosa (AN); and the first genome-wide
significant locus has been identified. We describe methods and procedures for the Anorexia …

[PDF][PDF] Autism-related dietary preferences mediate autism-gut microbiome associations

CX Yap, AK Henders, GA Alvares, DLA Wood… - Cell, 2021 - cell.com
There is increasing interest in the potential contribution of the gut microbiome to autism
spectrum disorder (ASD). However, previous studies have been underpowered and have not …

[HTML][HTML] Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

…, EM Byrne, SE Medland, DJ Statham, AK Henders… - Molecular …, 2012 - nature.com
Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology.
We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, …

Hypermetabolism in ALS is associated with greater functional decline and shorter survival

…, A Ceslis, S Heshmat, AK Henders… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective To determine the prevalence of hypermetabolism, relative to body composition, in
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …

Meta-analysis of genome-wide association studies of anxiety disorders

…, A Uitterlinden, CL Mulder, AK Henders… - Molecular …, 2016 - nature.com
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common,
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …