User profiles for A. K. Henders
Anjali HendersInstitute for Molecular Biosciences, The University of Queensland Verified email at uq.edu.au Cited by 29087 |
Common SNPs explain a large proportion of the heritability for human height
…, B Benyamin, BP McEvoy, S Gordon, AK Henders… - Nature …, 2010 - nature.com
SNPs discovered by genome-wide association studies (GWASs) account for only a small
fraction of the genetic variation of complex traits in human populations. Where is the remaining …
fraction of the genetic variation of complex traits in human populations. Where is the remaining …
Defining the role of common variation in the genomic and biological architecture of adult human height
…, NL Heard-Costa, Q Helmer, G Hemani, AK Henders… - Nature …, 2014 - nature.com
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …
significance that together explained one-fifth of the heritability for adult height. By testing …
[HTML][HTML] DNA methylation age of blood predicts all-cause mortality in later life
Background DNA methylation levels change with age. Recent studies have identified
biomarkers of chronological age based on DNA methylation levels. It is not yet known whether …
biomarkers of chronological age based on DNA methylation levels. It is not yet known whether …
Identification of seven loci affecting mean telomere length and their association with disease
…, K Garlaschelli, D Guo, AL Hartikainen, AK Henders… - Nature …, 2013 - nature.com
Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer
and several age-associated diseases. We report here a genome-wide meta-analysis of …
and several age-associated diseases. We report here a genome-wide meta-analysis of …
[HTML][HTML] The transcriptional landscape of age in human peripheral blood
Disease incidences increase with age, but the molecular characteristics of ageing that lead
to increased disease susceptibility remain inadequately understood. Here we perform a …
to increased disease susceptibility remain inadequately understood. Here we perform a …
The anorexia nervosa genetics initiative (ANGI): overview and methods
Background Genetic factors contribute to anorexia nervosa (AN); and the first genome-wide
significant locus has been identified. We describe methods and procedures for the Anorexia …
significant locus has been identified. We describe methods and procedures for the Anorexia …
[PDF][PDF] Autism-related dietary preferences mediate autism-gut microbiome associations
There is increasing interest in the potential contribution of the gut microbiome to autism
spectrum disorder (ASD). However, previous studies have been underpowered and have not …
spectrum disorder (ASD). However, previous studies have been underpowered and have not …
[HTML][HTML] Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned
Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology.
We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, …
We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, …
Hypermetabolism in ALS is associated with greater functional decline and shorter survival
…, A Ceslis, S Heshmat, AK Henders… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective To determine the prevalence of hypermetabolism, relative to body composition, in
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …
Meta-analysis of genome-wide association studies of anxiety disorders
…, A Uitterlinden, CL Mulder, AK Henders… - Molecular …, 2016 - nature.com
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common,
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …