User profiles for A. K. Pasupulati
AK Pasupulati, PA KumarUniversity of Hyderabad Verified email at uohyd.ac.in Cited by 2657 |
Neuroblastoma: Emerging trends in pathogenesis, diagnosis, and therapeutic targets
…, MK Pandey, SC Gupta, AK Pasupulati… - Journal of Controlled …, 2023 - Elsevier
Neuroblastoma (NB) accounts for about 13% of all pediatric cancer mortality and is the
leading cause of pediatric cancer death for children aged 1 to 5 years. NB, a developmental …
leading cause of pediatric cancer death for children aged 1 to 5 years. NB, a developmental …
[HTML][HTML] Novel actions of growth hormone in podocytes: implications for diabetic nephropathy
The kidney regulates water, electrolyte, and acid-base balance and thus maintains body
homeostasis. The kidney’s potential to ensure ultrafiltered and almost protein-free urine is …
homeostasis. The kidney’s potential to ensure ultrafiltered and almost protein-free urine is …
Detrimental effects of hypoxia on glomerular podocytes
Hypoxia-inducible factor1 (HIF1) plays a pivotal role in ensuring cells adapt to low-oxygen
conditions. Depletion of oxygen, a co-substrate during hydroxylation of prolyl (P402 and P564…
conditions. Depletion of oxygen, a co-substrate during hydroxylation of prolyl (P402 and P564…
[HTML][HTML] Advanced-glycation end-products induce podocyte injury and contribute to proteinuria
The prevalence of diabetes reaches epidemic proportions. Diabetes is the leading cause of
end-stage kidney disease (ESKD) since 30–40% of diabetic patients develop diabetic …
end-stage kidney disease (ESKD) since 30–40% of diabetic patients develop diabetic …
[HTML][HTML] Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy
Growth hormone (GH) plays a significant role in normal renal function and overactive GH
signaling has been implicated in proteinuria in diabetes and acromegaly. Previous results have …
signaling has been implicated in proteinuria in diabetes and acromegaly. Previous results have …
[HTML][HTML] Response of small heat shock proteins in diabetic rat retina
Purpose.: Small heat shock proteins (sHsps) have a critical role under stress conditions to
maintain cellular homeostasis by their involvement in protein-folding and cytoprotection. The …
maintain cellular homeostasis by their involvement in protein-folding and cytoprotection. The …
[HTML][HTML] Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria
…, K Chintala, P Tammineni, AK Pasupulati - Cell Death & …, 2021 - nature.com
Glomerular podocytes are integral members of the glomerular filtration barrier in the kidney
and are crucial for glomerular permselectivity. These highly differentiated cells are …
and are crucial for glomerular permselectivity. These highly differentiated cells are …
[HTML][HTML] Growth hormone induces transforming growth factor-β1 in podocytes: Implications in podocytopathy and proteinuria
…, S Maruvada, R Nishad, AK Pasupulati - … et Biophysica Acta (BBA …, 2023 - Elsevier
Pituitary growth hormone (GH) is essential for growth, metabolism, and renal function. Overactive
GH signaling is associated with impaired kidney function. Glomerular podocytes, a key …
GH signaling is associated with impaired kidney function. Glomerular podocytes, a key …
Hypoxia induces ZEB2 in podocytes: Implications in the pathogenesis of proteinuria
…, RK Menon, AK Pasupulati - Journal of cellular …, 2019 - Wiley Online Library
The glomerular filtration barrier (GFB) plays a critical role in ensuing protein free urine. The
integrity of the GFB is compromised during hypoxia that prevails during extreme …
integrity of the GFB is compromised during hypoxia that prevails during extreme …
Stabilization of hypoxia‐inducible factor 1α by cobalt chloride impairs podocyte morphology and slit‐diaphragm function
…, SK Mungamuri, AK Pasupulati - Journal of cellular …, 2019 - Wiley Online Library
Glomerular podocytes are the major components of the renal filtration barrier, and altered
podocyte permselectivity is a key event in the pathogenesis of proteinuric conditions. Clinical …
podocyte permselectivity is a key event in the pathogenesis of proteinuric conditions. Clinical …