To rapidly respond to invading microorganisms, humans call on their innate immune system.
This occurs by microbe‐detecting receptors, such as CD14, that activate immune cells to …

Hyperphosphorylated tau makes up the filamentous intracellular inclusions of several
neurodegenerative diseases, including Alzheimer's disease 1 . In the disease process, neuronal …

Emerging evidence points toward an intricate relationship between the pandemic of coronavirus
disease 2019 (COVID-19) and diabetes. While preexisting diabetes is associated with …

Therapy in patients with anti-MAG neuropathy is directed at reducing the antibody concentration,
blocking the effector mechanisms and depleting the monoclonal B cells. The recent …

In order to better understand the actions of proinflammatory cytokines in the mammalian CNS,
a transgenic approach was employed in which the expression of IL-6, IL-3 or TNF-α was …

… Stalder AK, Campbell IL: Simultaneous analysis of multiple cytokine receptor mRNAs by
RNase protection assay in LPS-induced endotoxemia. Lymphokine Cytokine Res 1994, 13:107-…

The significance of the peripheral immune system in Alzheimer's disease pathogenesis remains
controversial. To study the CNS invasion of hematopoietic cells in the course of cerebral …

Vaccine-based autoimmune (anti-amyloid) treatments are currently being examined for their
therapeutic potential in Alzheimer's disease. In the present study we examined, in a …

We describe Orbit Image Analysis, an open-source whole slide image analysis tool. The tool
consists of a generic tile-processing engine which allows the execution of various image …

It has been hypothesized that increased expression of proinflammatory cytokines mediate a
variety of central nervous system disorders such as multiple sclerosis, Alzheimer's disease, …