Understanding microbial gene functions relies on the application of experimental genetics
in cultured microorganisms. However, the vast majority of bacteria and archaea remain …

… 55 estudos dos cinco continentes, Moraes et al.observaram redução da prevalência de
hipertensão nos … específicos para cada medida estão descritos detalhadamente em Bloch et al.…

… Watters et al. and Marino et al. used bioinformatic and experimental approaches to identify
inhibitors of type V CRISPR-Cas12a. Cas12a has been successfully engineered for gene …

Bacteriophages from the Inoviridae family (inoviruses) are characterized by their unique
morphology, genome content and infection cycle. One of the most striking features of inoviruses …

Bacteria and archaea use CRISPR-Cas adaptive immune systems to defend themselves
from infection by bacteriophages (phages). These RNA-guided nucleases are powerful …

Bacteriophages (phages) are obligate parasites that use host bacterial translation machinery
to produce viral proteins. However, some phages have alternative genetic codes with …

Bacteria utilize CRISPR-Cas adaptive immune systems for protection from bacteriophages (phages),
and some phages produce anti-CRISPR (Acr) proteins that inhibit immune function. …

… Performing assays in the lysogenic state also allowed us to assess transcription levels at
a steady state as opposed to the dynamic situation existing during phage infection. Both the …

The CRISPR-Cas are adaptive bacterial and archaeal immunity systems that have been
harnessed for the development of powerful genome editing and engineering tools. In the …

Previous bioinformatic analyses of metagenomic data have indicated that bacteriophages
can use genetic codes different from those of their host bacteria. In particular, reassignment of …